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- W1594021705 abstract "Dopamine physiological activities are mediated by five distinct G proteins-coupled receptors. We have two types of receptors: D1-like (D1 and D5) and D2-like (D2, D3 and D4). D1-like receptors activate adenyl-cyclase and increase cAMP whereas the later activate K+ channels hyperpolarizing the post-synaptic cell. There are some variants of these receptors according to alternative splicing and to the occurrence of pseudogenes and polymorphisms of the genes that codify receptor structures. However, most of them are inactive or functionless. Dopamine receptors are extensively expressed in CNS and are involved in motor control, cognitive, emotive and affective activities and also in neuroen-" @default.
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- W1594021705 date "2002-01-01" @default.
- W1594021705 modified "2023-09-23" @default.
- W1594021705 title "Receptores da dopamina eesquizofrenia" @default.
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