FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1594138001> ?p ?o ?g. }

• W1594138001 endingPage "42" @default.
• W1594138001 startingPage "9" @default.
• W1594138001 abstract "Meister's proposal of a gamma-glutamyl-P intermediate in the glutamine synthetase reaction set the scene for understanding how the stepwise activation of the carboxyl group greatly increased its susceptibility toward nucleophilic attack and amide bond synthesis. Topics covered in this review include: the discovery of the enzymatic synthesis of glutamine; the role of glutamine synthetase in defining the thermodynamics of ATPases; early isotopic tracer studies of the synthetase reaction; the proposed intermediacy of gamma-glutamyl-phosphate; the mechanism of methionine sulfoximine inhibition; stereochemical mapping of the enzyme's active site; detection of enzyme reaction cycle intermediates; borohydride trapping of gamma-glutamyl-P; positional isotope exchanges catalyzed by glutamine synthetase; regulation of bacterial enzyme; and a brief account of how knowledge of the atomic structure of bacterial glutamine synthetase has clarified ligand binding interactions. Concluding remarks also address how the so-called Protein Ligase Problem may be solved by extending the catalytic versatility of carboxyl-group activating enzymes." @default.
• W1594138001 created "2016-06-24" @default.
• W1594138001 creator A5054730579 @default.
• W1594138001 date "1998-01-01" @default.
• W1594138001 modified "2023-10-16" @default.
• W1594138001 title "Advances in the Enzymology of Glutamine Synthesis" @default.
• W1594138001 cites W1029426564 @default.
• W1594138001 cites W114952891 @default.
• W1594138001 cites W115724639 @default.
• W1594138001 cites W1492542444 @default.
• W1594138001 cites W1493077871 @default.
• W1594138001 cites W1506233309 @default.
• W1594138001 cites W1520565605 @default.
• W1594138001 cites W1535979687 @default.
• W1594138001 cites W1555498397 @default.
• W1594138001 cites W1557790290 @default.
• W1594138001 cites W1571275312 @default.
• W1594138001 cites W1573147813 @default.
• W1594138001 cites W1578684139 @default.
• W1594138001 cites W1588519390 @default.
• W1594138001 cites W1593565868 @default.
• W1594138001 cites W1599232083 @default.
• W1594138001 cites W1629628005 @default.
• W1594138001 cites W1633567371 @default.
• W1594138001 cites W180945327 @default.
• W1594138001 cites W1864266030 @default.
• W1594138001 cites W190762827 @default.
• W1594138001 cites W1965844459 @default.
• W1594138001 cites W1968266936 @default.
• W1594138001 cites W1969423770 @default.
• W1594138001 cites W1971185229 @default.
• W1594138001 cites W1977051051 @default.
• W1594138001 cites W1986085513 @default.
• W1594138001 cites W2004311740 @default.
• W1594138001 cites W2009527472 @default.
• W1594138001 cites W2014781793 @default.
• W1594138001 cites W2030539003 @default.
• W1594138001 cites W2032931308 @default.
• W1594138001 cites W2034335419 @default.
• W1594138001 cites W2035778257 @default.
• W1594138001 cites W2037778165 @default.
• W1594138001 cites W2040344830 @default.
• W1594138001 cites W2048588519 @default.
• W1594138001 cites W2056062154 @default.
• W1594138001 cites W2061120858 @default.
• W1594138001 cites W2061317980 @default.
• W1594138001 cites W2067462759 @default.
• W1594138001 cites W2072326645 @default.
• W1594138001 cites W2091473682 @default.
• W1594138001 cites W2122865644 @default.
• W1594138001 cites W2132648351 @default.
• W1594138001 cites W2161011670 @default.
• W1594138001 cites W2165362892 @default.
• W1594138001 cites W2258854900 @default.
• W1594138001 cites W2301522081 @default.
• W1594138001 cites W2334475434 @default.
• W1594138001 cites W3826624 @default.
• W1594138001 cites W4213262935 @default.
• W1594138001 cites W4250902882 @default.
• W1594138001 cites W73242948 @default.
• W1594138001 cites W74811512 @default.
• W1594138001 doi "https://doi.org/10.1002/9780470123188.ch2" @default.
• W1594138001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9559050" @default.
• W1594138001 hasPublicationYear "1998" @default.
• W1594138001 type Work @default.
• W1594138001 sameAs 1594138001 @default.
• W1594138001 citedByCount "14" @default.
• W1594138001 countsByYear W15941380012013 @default.
• W1594138001 countsByYear W15941380012016 @default.
• W1594138001 countsByYear W15941380012022 @default.
• W1594138001 countsByYear W15941380012023 @default.
• W1594138001 crossrefType "other" @default.
• W1594138001 hasAuthorship W1594138001A5054730579 @default.
• W1594138001 hasConcept C105768512 @default.
• W1594138001 hasConcept C161790260 @default.
• W1594138001 hasConcept C175114707 @default.
• W1594138001 hasConcept C178790620 @default.
• W1594138001 hasConcept C178907741 @default.
• W1594138001 hasConcept C181199279 @default.
• W1594138001 hasConcept C185592680 @default.
• W1594138001 hasConcept C2779289688 @default.
• W1594138001 hasConcept C2779349466 @default.
• W1594138001 hasConcept C36674120 @default.
• W1594138001 hasConcept C515207424 @default.
• W1594138001 hasConcept C55493867 @default.
• W1594138001 hasConcept C63338738 @default.
• W1594138001 hasConcept C71240020 @default.
• W1594138001 hasConceptScore W1594138001C105768512 @default.
• W1594138001 hasConceptScore W1594138001C161790260 @default.
• W1594138001 hasConceptScore W1594138001C175114707 @default.
• W1594138001 hasConceptScore W1594138001C178790620 @default.
• W1594138001 hasConceptScore W1594138001C178907741 @default.
• W1594138001 hasConceptScore W1594138001C181199279 @default.
• W1594138001 hasConceptScore W1594138001C185592680 @default.
• W1594138001 hasConceptScore W1594138001C2779289688 @default.
• W1594138001 hasConceptScore W1594138001C2779349466 @default.
• W1594138001 hasConceptScore W1594138001C36674120 @default.
• W1594138001 hasConceptScore W1594138001C515207424 @default.

• next