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• W1594575175 abstract "The human organism continuously takes up nutrients to build up macromolecules and functionally active structures. On the basis of the first law of thermodynamics, the energy of nutrients is transformed, proceeding toward minimum entropy production and the release of heat and “waste products” in the open system. Part of the heat produced during exothermic processes supports the optimal efficiency of the endothermic biological reactions in the organism, and the rest is dissipated in the environment on the basis of the Second Law of Thermodynamics. In contrast with the living state, cancers live on the energy and mass of the organism as a parasite metabolizing and destroying the tissues of the organism according to the Second Law of Thermodynamics. Schroedinger put the question of whether life is based on the laws of physics. He suggested that: chemical processes lead to entropy production, which is a direct measure of molecular disorder (1). At the end of his book, he summarized his view: “We must therefore not be discouraged by the difficulty in interpreting life by the ordinary laws of physics” (1). Where processes under conditions far from equilibrium correspond to an interplay between chance and necessity, between deterministic laws and fluctuations (2, 3). During tumor growth, there are many differences between the healthy tissues and the growing tumor, including metabolic, structural and thermodynamic differences, for heat production. Both structural differences and heat formation can be used to follow the entropy differences between cancerous and nomal tissues. These entropy changes can be followed by various methods, e.g. histology and thermography. In general, the calculation of entropy production due to thermal fluxes based on temperature differences and, similarly, differences in other entropy-producing processes as driving forces are promising as potential targets for tumor demarcation (2-4)." @default.
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• W1594575175 date "2011-01-14" @default.
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• W1594575175 title "The Second Law of Thermodynamics and Host-Tumor Relationships: Concepts and Opportunities" @default.
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• W1594575175 doi "https://doi.org/10.5772/12973" @default.
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