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• W1594588946 abstract "The transduction efficiency of human bone marrow CD34+ cells with supernatants from the retrovirus producer cell clone PA317/LGSN 16 was only one-fifth of that with supernatants from GP+ envAm12/LGSN 15, even though both producers had similar infection titers on 3T3 cells. PA317/LGSN 16-conditioned medium inhibited the proliferation of the bone marrow CD34+ cells, and this inhibitory effect was partially blocked by anti-transforming growth factor beta antibodies. These studies suggest that cytokine secretion plays a role in the suppression of retrovirus transduction of human CD34+ cells." @default.
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• W1594588946 date "1994-11-01" @default.
• W1594588946 modified "2023-09-27" @default.
• W1594588946 title "Poor transduction efficiency of human hematopoietic progenitor cells by a high-titer amphotropic retrovirus producer cell clone" @default.
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• W1594588946 doi "https://doi.org/10.1128/jvi.68.11.7634-7636.1994" @default.
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