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- W1594751421 abstract "Abstract The anti-ld response developed by cynomolgus monkeys to the humanized anti-Tac antibody was analyzed by using 12 humanized anti-Tac variants differing in V region structure. The majority of the monkey response was directed against idiotopes composed wholly or in part of complementarity-determining regions H1, H2, and L3. There was no detectable response directed solely to five single complementarity-determining regions examined or solely to the modified human V region framework." @default.
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- W1594751421 date "1993-04-01" @default.
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- W1594751421 title "The anti-idiotypic response by cynomolgus monkeys to humanized anti-Tac is primarily directed to complementarity-determining regions H1, H2, and L3." @default.
- W1594751421 doi "https://doi.org/10.4049/jimmunol.150.7.3086" @default.
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