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- W1594991922 abstract "Abstract 4-Valine-oxytocin and 1-deamino-4-valine-oxytocin, analogues of the posterior pituitary hormone containing a valine residue in place of the glutamine residue in position 4, have been synthesized by the p-nitrophenyl ester method of peptide synthesis and tested for pharmacological activity. The 4-valine-oxytocin possesses 140 units per mg of oxytocic activity and 240 units per mg of avian vasodepressor activity. The 1-deamino-4-valine-oxytocin, in which the free amino group on the half-cystine residue in position 1 of 4-valine-oxytocin is replaced by hydrogen, is a highly potent compound, possessing approximately 350 units of oxytocic activity and 800 units of avian vasodepressor activity per mg." @default.
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- W1594991922 date "1966-05-01" @default.
- W1594991922 modified "2023-09-28" @default.
- W1594991922 title "Synthesis and Some Biological Properties of 4-Valine-oxytocin and 1-Deamino-4-valine-oxytocin" @default.
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- W1594991922 doi "https://doi.org/10.1016/s0021-9258(18)96670-6" @default.
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