Matches in SemOpenAlex for { <https://semopenalex.org/work/W1595382395> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1595382395 endingPage "1175" @default.
- W1595382395 startingPage "1170" @default.
- W1595382395 abstract "Purpose The local injection of neurotransmitter agonists and antagonists to modulate recorded neurons in awake animals has long been an important and widely used technique in neuroscience. Combined with functional magnetic resonance imaging (fMRI) and simultaneous electrophysiology, local injection enables the study of specific brain regions under precise modulations of their neuronal activity. However, localized injections are often accompanied by mechanical displacement of the tissue, known as volume effect (VE), which can induce changes in electrophysiological recordings as well as artifacts that are particular to fMRI studies. Methods We characterize the changes produced by VE in an agarose phantom as well as during stimulus-evoked and resting-state fMRI and simultaneously acquired electrophysiology in awake rabbits. Results Our results demonstrate that localized injection can produce significant intensity changes in fMRI data, even while effects on electrophysiological recordings are minimized. These changes are localized to the vicinity of the injection needle and diminish over time due to diffusion of the injected volume. Conclusion Sufficient time should be allowed for drug diffusion to ensure stable results, particularly for resting-state fMRI experiments. Magn Reson Med 72:1170–1175, 2014. © 2013 Wiley Periodicals, Inc." @default.
- W1595382395 created "2016-06-24" @default.
- W1595382395 creator A5007697293 @default.
- W1595382395 creator A5035626682 @default.
- W1595382395 creator A5040850123 @default.
- W1595382395 creator A5042319547 @default.
- W1595382395 creator A5063434268 @default.
- W1595382395 date "2013-10-29" @default.
- W1595382395 modified "2023-10-03" @default.
- W1595382395 title "Volume effect of localized injection in functional MRI and electrophysiology" @default.
- W1595382395 cites W1966535458 @default.
- W1595382395 cites W1978293219 @default.
- W1595382395 cites W2020171905 @default.
- W1595382395 cites W2035595295 @default.
- W1595382395 cites W2054771039 @default.
- W1595382395 cites W2057092726 @default.
- W1595382395 cites W2057377744 @default.
- W1595382395 cites W2062990740 @default.
- W1595382395 cites W2082377728 @default.
- W1595382395 cites W2087057112 @default.
- W1595382395 cites W2106495485 @default.
- W1595382395 cites W2109452918 @default.
- W1595382395 cites W2137231621 @default.
- W1595382395 cites W4253012755 @default.
- W1595382395 doi "https://doi.org/10.1002/mrm.24996" @default.
- W1595382395 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24273205" @default.
- W1595382395 hasPublicationYear "2013" @default.
- W1595382395 type Work @default.
- W1595382395 sameAs 1595382395 @default.
- W1595382395 citedByCount "6" @default.
- W1595382395 countsByYear W15953823952016 @default.
- W1595382395 countsByYear W15953823952019 @default.
- W1595382395 countsByYear W15953823952022 @default.
- W1595382395 countsByYear W15953823952023 @default.
- W1595382395 crossrefType "journal-article" @default.
- W1595382395 hasAuthorship W1595382395A5007697293 @default.
- W1595382395 hasAuthorship W1595382395A5035626682 @default.
- W1595382395 hasAuthorship W1595382395A5040850123 @default.
- W1595382395 hasAuthorship W1595382395A5042319547 @default.
- W1595382395 hasAuthorship W1595382395A5063434268 @default.
- W1595382395 hasBestOaLocation W15953823951 @default.
- W1595382395 hasConcept C126838900 @default.
- W1595382395 hasConcept C143409427 @default.
- W1595382395 hasConcept C15744967 @default.
- W1595382395 hasConcept C169760540 @default.
- W1595382395 hasConcept C185263204 @default.
- W1595382395 hasConcept C185592680 @default.
- W1595382395 hasConcept C2779226451 @default.
- W1595382395 hasConcept C2779918689 @default.
- W1595382395 hasConcept C542102704 @default.
- W1595382395 hasConcept C66324658 @default.
- W1595382395 hasConcept C71924100 @default.
- W1595382395 hasConceptScore W1595382395C126838900 @default.
- W1595382395 hasConceptScore W1595382395C143409427 @default.
- W1595382395 hasConceptScore W1595382395C15744967 @default.
- W1595382395 hasConceptScore W1595382395C169760540 @default.
- W1595382395 hasConceptScore W1595382395C185263204 @default.
- W1595382395 hasConceptScore W1595382395C185592680 @default.
- W1595382395 hasConceptScore W1595382395C2779226451 @default.
- W1595382395 hasConceptScore W1595382395C2779918689 @default.
- W1595382395 hasConceptScore W1595382395C542102704 @default.
- W1595382395 hasConceptScore W1595382395C66324658 @default.
- W1595382395 hasConceptScore W1595382395C71924100 @default.
- W1595382395 hasIssue "4" @default.
- W1595382395 hasLocation W15953823951 @default.
- W1595382395 hasLocation W15953823952 @default.
- W1595382395 hasOpenAccess W1595382395 @default.
- W1595382395 hasPrimaryLocation W15953823951 @default.
- W1595382395 hasRelatedWork W159517055 @default.
- W1595382395 hasRelatedWork W1964455563 @default.
- W1595382395 hasRelatedWork W2168298321 @default.
- W1595382395 hasRelatedWork W2294986132 @default.
- W1595382395 hasRelatedWork W2365200835 @default.
- W1595382395 hasRelatedWork W2365936003 @default.
- W1595382395 hasRelatedWork W2387620927 @default.
- W1595382395 hasRelatedWork W2390151142 @default.
- W1595382395 hasRelatedWork W2601707947 @default.
- W1595382395 hasRelatedWork W4283218783 @default.
- W1595382395 hasVolume "72" @default.
- W1595382395 isParatext "false" @default.
- W1595382395 isRetracted "false" @default.
- W1595382395 magId "1595382395" @default.
- W1595382395 workType "article" @default.