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- W1595650437 abstract "Oligodendroglial tumors: correlation between tumor genotype and perfusion magnetic resonance imaging Objective: To perform a retrospective assessment of the cor- relation between perfusion MR imaging, relative cerebral blood volume (rCBV) and genotype in patients with grade II oligodendroglial neoplasms. Materials and methods: Eleven patients (7 men and 4 women), age range: 28-64 years, with grade II oligoden- droglial tumors (OD) were studied using conventional MR and perfusion MR imaging (rCBV). Genetic analysis was carried out in all patients to assess -1p/-19q genotype status. Results: Five patients with grade II oligodendroglial tumors (45%) presented rCBV 1.75 in two patients and 1.75, one with intact 1p/19q, and the other with deletion. The last patient presented a grade II oligodendroglial tumor with rCBV < 1.75 and 1p/19q loss. Conclusions: Approximately 45% of patients with intact 1p/19q showed rCBV < 1.75, suggesting limited tumor neoangiogenesis. These findings could be important for the antiangiogenic therapy follow-up. Studies in larger series could provide valuable information prior to surgery and contribute to a better management of these patients." @default.
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- W1595650437 date "2011-03-01" @default.
- W1595650437 modified "2023-09-23" @default.
- W1595650437 title "Tumores oligodendrogliales: correlación entre el genotipo tumoral e imágenes de perfusión por RM" @default.
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