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- W159568488 endingPage "532" @default.
- W159568488 startingPage "507" @default.
- W159568488 abstract "Hyperandrogenism must be considered in any girl with premature pubarche, unusual acne, hirsutism, or androgenetic alopecia. An association with menstrual irregularity or obesity should raise the index of suspicion. The most common causes of hyperandrogenism presenting in a teenage girl are functional ovarian hyperandrogenism, one manifestation of which is polycystic ovary syndrome, and functional adrenal hyperandrogenism, which usually seems to be due to an exaggeration of adrenarche. The plasma-free testosterone is a more sensitive indicator of hyperandrogenism than is the total testosterone concentration. The pattern of response of plasma free testosterone, DHEAS, and cortisol to dex-suppression testing can be diagnostic of the source of androgen excess. Treatment, including oral contraceptives, low-dose glucocorticoids, and antiandrogens, should be chosen according to the patient's symptoms and source of androgens and should be combined with traditional therapy for the specific dermatologic disorder." @default.
- W159568488 created "2016-06-24" @default.
- W159568488 creator A5006387457 @default.
- W159568488 creator A5010901410 @default.
- W159568488 date "1993-09-01" @default.
- W159568488 modified "2023-09-26" @default.
- W159568488 title "Acne, Hirsutism, and Alopecia in Adolescent Girls: Clinical Expressions of Androgen Excess" @default.
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- W159568488 doi "https://doi.org/10.1016/s0889-8529(18)30148-8" @default.
- W159568488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8243445" @default.
- W159568488 hasPublicationYear "1993" @default.
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