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• W1595702494 abstract "Objectives We evaluated healing responses with optical coherence tomography (OCT), and clinical and angiographic outcome after bifurcation stenting with the TRYTON Side-Branch Stent™. Background Dedicated bifurcation stents have been proposed as a potential alternative for treatment of true coronary bifurcation lesions. Methods We treated 20 consecutive patients with coronary bifurcation lesions and significant involvement of the side-branch (SB) with the TRYTON Stent and an additional XIENCE-V™ everolimus-eluting stent. At 9 months, we assessed the ratio of uncovered to total stent struts (RUTSS) with OCT, angiographic late luminal loss (LLL), and in-stent and in-segment restenosis. Clinical endpoints at 1 year included major adverse cardiac events (MACE) and their components [target lesion revascularization (TLR), myocardial infarction (MI), and cardiac death]. Results LLL (N = 16) was 0.34 (0.17–0.46), 0.29 (0.24–0.48) and 0.57 (0.29–0.73) mm in the proximal main vessel (MV), distal MV and SB, respectively. In-bifurcation binary in-stent restenosis occurred in four patients (25%), in-segment restenosis in five (31.25%). The RUTSS (N = 13) was 4.0 ± 5.8, 0.7 ± 1.3, 0, and 2.5 ± 3.6% in the proximal MV, distal MV, SB, and polygon of confluence, respectively. At 1 year, MACE occurred in 5 (25%) [4 TLR (20%), 3 MI (15%)]. Conclusion The homogeneous stent strut coverage and the low LLL in the MV reflect proper healing characteristics of the TRYTON Stent in combination with the XIENCE-V™ stent. However, proximal MV edge and ostial SB restenoses together with overall clinical outcomes do not fulfill expectations of a dedicated bifurcation stent. © 2012 Wiley Periodicals, Inc." @default.
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• W1595702494 date "2012-11-14" @default.
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• W1595702494 title "Healing responses after bifurcation stenting with the dedicated TRYTON side-branch stent™ in combination with XIENCE-V™ stents: A clinical, angiography, fractional flow reserve, and optical coherence tomography study: The PYTON (Prospective evaluation of" @default.
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• W1595702494 doi "https://doi.org/10.1002/ccd.24536" @default.
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