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• W1595833989 endingPage "619" @default.
• W1595833989 startingPage "317" @default.
• W1595833989 abstract "Recent definitions of episodic memory point out that it consists of autobiographical events with a clear time, space and context relation, usually having an emotional tone and a relation to one's own self. In this contribution, we summarize the role of the prefrontal cortex in episodic memory encoding and retrieval and related functions. We demonstrate that the dorsolateral portion is predominantly associated with monitoring encoding and retrieval processes. The ventrolateral prefrontal region is linked to strategic retrieval and information selection as well as verification of content to be retrieved. It is also engaged in triggering autobiographical memory retrieval by synchronizing emotional and factual components of the personal past. In the integration of the emotional connotation of memories, the ventromedial prefrontal region is critically involved. The dorsomedial prefrontal cortex is the main region contributing to self-referential processing and is therefore necessarily involved in episodic memory, as remembering one's own biography fundamentally depends on a feeling of one's own self. In the second part, we describe dysfunctions of autobiographical-episodic memory due to brain damage or in the cause of dissociative amnesia. We give examples emphasizing the assumption that malfunction of prefrontal cortex regions can explain the retrieval deficits both in patients with organic amnesia and in those individuals who suffer from retrograde amnesia in the absence of structural brain changes." @default.
• W1595833989 created "2016-06-24" @default.
• W1595833989 creator A5013898044 @default.
• W1595833989 creator A5036700773 @default.
• W1595833989 date "2008-01-01" @default.
• W1595833989 modified "2023-09-25" @default.
• W1595833989 title "Chapter 3.5 The role of the prefrontal cortex in episodic memory" @default.
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