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- W1596292401 abstract "This chapter deals with issues of fitting data to models and assessing validity using independent data. When animal data are used, it is particularly important to perform validation by comparison with outbreak investigations. The chapter address this issue of validation. It considers a very little prior work on the presence of outliers and their implications in dose–response data. The chapter discusses quantitative approaches to assess risk from multiple exposures. It focuses on the description of the relationship between dose and probability of infection and direct use of pathogens to assess dose–response and ultimately risk. A dose–response relationship is formulated using indicators systems that have been developed from epidemiologic studies. The models discussed in this chapter predict the proportion of individuals succumbing to an effect as a result of an exposure and perhaps the severity (infection, morbidity, mortality) of the outcome." @default.
- W1596292401 created "2016-06-24" @default.
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- W1596292401 date "2014-06-13" @default.
- W1596292401 modified "2023-10-14" @default.
- W1596292401 title "Conducting the Dose–Response Assessment" @default.
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- W1596292401 doi "https://doi.org/10.1002/9781118910030.ch8" @default.
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