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- W1596305087 abstract "In oncology drug development, it is important to develop low risk drugs efficiently. Meanwhile, computational methods have been paid more and more attention in drug discovery. However, few studies attempt to discover the mutual gene modules shared by the drug and disease association. Here we introduce a novel method to identify repositioned drug for breast cancer by integrating the breast cancer survival data with the drug sensitivity information. Among the 140 drug candidates, we are able to filter 4 FDA approved drugs and identify 2 breast cancer drugs among 4 known breast cancer therapeutic drug in total." @default.
- W1596305087 created "2016-06-24" @default.
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- W1596305087 date "2015-05-29" @default.
- W1596305087 modified "2023-09-26" @default.
- W1596305087 title "Identification association of drug-disease by using functional gene module for breast cancer" @default.
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- W1596305087 doi "https://doi.org/10.1186/1755-8794-8-s2-s3" @default.
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