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- W1596423576 abstract "Aim: We aimed to compare the clinical results and effectiveness of two gonadothropin treatment protocols;HP-uFSH and rFSH in poor responders.Materials and Methods: While HP-uFSH was given to 58 patients, rFSH was given to 62 patients. The patientselection criteria were the same (FSH value > 15 iu/l or antral follicle number < 4, on the second day of menstruation).Results: Endometrial thickness on hCG day (mm) was 9.0 ± 2.7 and 7.8 ± 2.7 in HP-uFSH group and rFSH group, respectively and this difference was statistically significant. Contrarily, fertilization rate (%) was better in rFSH than HP-uFSH (76.6 ± 15.9 vs. 68.2 ± 17.8) and this value was also statistically significant. Percentage of cancelled cycles (%) was 14 ± 34 in HP-uFSH group and this parameter was significantly lower than rFSH group (29 ± 45).Conclusion: rFSH is as efficacious as HP-uFSH in poor responders. Fertilization rate was better in rFSH than HP-uFSH. Since rFSH is more expensive, the final treatment cost with rFSH to obtain a pregnancy was slightly higher, but this difference was not statistically significant (20060 TL vs. 17150 TL)." @default.
- W1596423576 created "2016-06-24" @default.
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- W1596423576 date "2011-08-28" @default.
- W1596423576 modified "2023-10-16" @default.
- W1596423576 title "Comparison of the Efficacy and Cost-effectiveness of Highly Purified Urinary Follicle Stimulating Hormone (HP-uFSH) and Recombinant Follicle Stimulating Hormone (rFSH) in Poor Responders" @default.
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