FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1596969552> ?p ?o ?g. }

• W1596969552 endingPage "9" @default.
• W1596969552 startingPage "2" @default.
• W1596969552 abstract "The biological mechanisms responsible for the pathophysiology of the Wiskott–Aldrich syndrome (WAS) have been shown to be linked to the regulation of actin polymerization in haematopoietic cells. WAS protein (WASp) is now known to be a member of a unique family sharing similar domain structures, which are responsible for transduction of signals from the cell membrane to the actin cytoskeleton. The interaction between WASp, the Rho family GTPase CDC42, and the cytoskeletal organising complex Arp2/3 is probably critical to many of these functions, which when disturbed translate into measurable defects of cell signalling, polarization, motility, and phagocytosis. These recent findings provide additional clues as to the nature of the immunodeficiency of WAS, and ultimately may guide the development of more diverse and effective therapeutic strategies." @default.
• W1596969552 created "2016-06-24" @default.
• W1596969552 creator A5015856478 @default.
• W1596969552 creator A5080762141 @default.
• W1596969552 date "2000-04-01" @default.
• W1596969552 modified "2023-09-25" @default.
• W1596969552 title "The Wiskott–Aldrich syndrome" @default.
• W1596969552 cites W1218487485 @default.
• W1596969552 cites W1481442945 @default.
• W1596969552 cites W1497033324 @default.
• W1596969552 cites W1520402351 @default.
• W1596969552 cites W1524475817 @default.
• W1596969552 cites W1530654031 @default.
• W1596969552 cites W1532545761 @default.
• W1596969552 cites W1575892864 @default.
• W1596969552 cites W1597182573 @default.
• W1596969552 cites W1969172568 @default.
• W1596969552 cites W1973077682 @default.
• W1596969552 cites W1974675292 @default.
• W1596969552 cites W1975784948 @default.
• W1596969552 cites W1977250201 @default.
• W1596969552 cites W1979713589 @default.
• W1596969552 cites W1991229933 @default.
• W1596969552 cites W1993238790 @default.
• W1596969552 cites W2000362479 @default.
• W1596969552 cites W2005216911 @default.
• W1596969552 cites W2006996074 @default.
• W1596969552 cites W2007293710 @default.
• W1596969552 cites W2016253390 @default.
• W1596969552 cites W2016459259 @default.
• W1596969552 cites W2017239868 @default.
• W1596969552 cites W2018317768 @default.
• W1596969552 cites W2021292007 @default.
• W1596969552 cites W2025138357 @default.
• W1596969552 cites W2025459204 @default.
• W1596969552 cites W2027810531 @default.
• W1596969552 cites W2031123547 @default.
• W1596969552 cites W2033619721 @default.
• W1596969552 cites W2035589350 @default.
• W1596969552 cites W2036145275 @default.
• W1596969552 cites W2040081026 @default.
• W1596969552 cites W2042151587 @default.
• W1596969552 cites W2043646282 @default.
• W1596969552 cites W2045923054 @default.
• W1596969552 cites W2047721998 @default.
• W1596969552 cites W2049811440 @default.
• W1596969552 cites W2054993296 @default.
• W1596969552 cites W2061714417 @default.
• W1596969552 cites W2061891312 @default.
• W1596969552 cites W2068669952 @default.
• W1596969552 cites W2072556964 @default.
• W1596969552 cites W2076118496 @default.
• W1596969552 cites W2076808220 @default.
• W1596969552 cites W2078384542 @default.
• W1596969552 cites W2079099921 @default.
• W1596969552 cites W2083197627 @default.
• W1596969552 cites W2088618181 @default.
• W1596969552 cites W2093844155 @default.
• W1596969552 cites W2107625881 @default.
• W1596969552 cites W2111528051 @default.
• W1596969552 cites W2112600997 @default.
• W1596969552 cites W2113249117 @default.
• W1596969552 cites W2120425861 @default.
• W1596969552 cites W2121889667 @default.
• W1596969552 cites W2122782850 @default.
• W1596969552 cites W2134073082 @default.
• W1596969552 cites W2134855648 @default.
• W1596969552 cites W2135369362 @default.
• W1596969552 cites W2136611642 @default.
• W1596969552 cites W2147359514 @default.
• W1596969552 cites W2148473582 @default.
• W1596969552 cites W2153482320 @default.
• W1596969552 cites W2157815908 @default.
• W1596969552 cites W2158726454 @default.
• W1596969552 cites W2164988883 @default.
• W1596969552 cites W2165364837 @default.
• W1596969552 cites W2171303172 @default.
• W1596969552 cites W2262065180 @default.
• W1596969552 cites W2292795665 @default.
• W1596969552 cites W2323022327 @default.
• W1596969552 cites W2338046092 @default.
• W1596969552 cites W2406847804 @default.
• W1596969552 cites W2416378933 @default.
• W1596969552 cites W2418072786 @default.
• W1596969552 cites W2463797415 @default.
• W1596969552 cites W2515687118 @default.
• W1596969552 cites W338475641 @default.
• W1596969552 cites W4235415764 @default.
• W1596969552 cites W4297040010 @default.
• W1596969552 cites W74607343 @default.
• W1596969552 cites W77948366 @default.
• W1596969552 doi "https://doi.org/10.1046/j.1365-2249.2000.01193.x" @default.
• W1596969552 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1905602" @default.
• W1596969552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10759756" @default.
• W1596969552 hasPublicationYear "2000" @default.
• W1596969552 type Work @default.
• W1596969552 sameAs 1596969552 @default.
• W1596969552 citedByCount "47" @default.

• next