FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1597017789> ?p ?o ?g. }

• W1597017789 endingPage "66" @default.
• W1597017789 startingPage "53" @default.
• W1597017789 abstract "In the past decade a great deal of success has been achieved in our understanding of the neurobiological basis of depressive syndromes. Genetic factors, structural changes and neuronal networks, which are important in generating pathological cognitive processes, emotional and behavioral patterns have been identified and characterized. These findings have lead to an improvement in therapeutic interventions and drug therapy. Risk factors have been described thus allowing the early detection of affective disorders. At present the main focus of research is to gain greater understanding of the functional polymorphism in the serotonin transporter promoter region. Furthermore, the genetic basis of neurotoxic and neuroprotective processes (neurotrophic factors) and their relation to anatomical changes are being examined. The functional polymorphism in the serotonin transporter promoter region increases stress-related vulnerability which has been found to be associated with a higher risk for affective disorders. Structural and functional neuroimaging of the amygdala, hippocampus and the prefrontal cortex allow detailed descriptions of morphological changes. Imbalances in different neurotransmitter systems and factors modulating monoamine receptor sensitivity have been characterized and their correlations with genetic, structural and psychosocial factors influencing depressive syndromes are being studied. Research in the field of etiology and pathogenesis of the disease has lead to considerable advances in our understanding of developmental neurobiology, the vulnerability and resiliency of the young patient, and has improved the possibility of intervention at an early stage of the disease. These pathogenetic mechanisms including genetic causes, morphological correlates and the resulting functional consequences are outlined." @default.
• W1597017789 created "2016-06-24" @default.
• W1597017789 creator A5045006378 @default.
• W1597017789 creator A5070900033 @default.
• W1597017789 date "2008-01-01" @default.
• W1597017789 modified "2023-09-24" @default.
• W1597017789 title "Neurobiology of Depression in Childhood and Adolescence" @default.
• W1597017789 cites W1964819394 @default.
• W1597017789 cites W1977866915 @default.
• W1597017789 cites W1999380874 @default.
• W1597017789 cites W2014643424 @default.
• W1597017789 cites W2020897240 @default.
• W1597017789 cites W2023777866 @default.
• W1597017789 cites W2044710410 @default.
• W1597017789 cites W2056796420 @default.
• W1597017789 cites W2057008284 @default.
• W1597017789 cites W2059389633 @default.
• W1597017789 cites W2061730652 @default.
• W1597017789 cites W2075049994 @default.
• W1597017789 cites W2076246669 @default.
• W1597017789 cites W2082772986 @default.
• W1597017789 cites W2089694176 @default.
• W1597017789 cites W2091534785 @default.
• W1597017789 cites W2105874139 @default.
• W1597017789 cites W2110116395 @default.
• W1597017789 cites W2120032880 @default.
• W1597017789 cites W2120296839 @default.
• W1597017789 cites W2120607580 @default.
• W1597017789 cites W2125901028 @default.
• W1597017789 cites W2147351252 @default.
• W1597017789 cites W2161085199 @default.
• W1597017789 cites W2162196924 @default.
• W1597017789 cites W2399288269 @default.
• W1597017789 cites W2601386298 @default.
• W1597017789 doi "https://doi.org/10.1159/000118516" @default.
• W1597017789 hasPublicationYear "2008" @default.
• W1597017789 type Work @default.
• W1597017789 sameAs 1597017789 @default.
• W1597017789 citedByCount "1" @default.
• W1597017789 countsByYear W15970177892022 @default.
• W1597017789 crossrefType "book-chapter" @default.
• W1597017789 hasAuthorship W1597017789A5045006378 @default.
• W1597017789 hasAuthorship W1597017789A5070900033 @default.
• W1597017789 hasConcept C118552586 @default.
• W1597017789 hasConcept C138496976 @default.
• W1597017789 hasConcept C139719470 @default.
• W1597017789 hasConcept C15744967 @default.
• W1597017789 hasConcept C162324750 @default.
• W1597017789 hasConcept C2776867660 @default.
• W1597017789 hasConceptScore W1597017789C118552586 @default.
• W1597017789 hasConceptScore W1597017789C138496976 @default.
• W1597017789 hasConceptScore W1597017789C139719470 @default.
• W1597017789 hasConceptScore W1597017789C15744967 @default.
• W1597017789 hasConceptScore W1597017789C162324750 @default.
• W1597017789 hasConceptScore W1597017789C2776867660 @default.
• W1597017789 hasLocation W15970177891 @default.
• W1597017789 hasOpenAccess W1597017789 @default.
• W1597017789 hasPrimaryLocation W15970177891 @default.
• W1597017789 hasRelatedWork W1511810905 @default.
• W1597017789 hasRelatedWork W1969392677 @default.
• W1597017789 hasRelatedWork W2049115098 @default.
• W1597017789 hasRelatedWork W2088525127 @default.
• W1597017789 hasRelatedWork W2141747781 @default.
• W1597017789 hasRelatedWork W2143869620 @default.
• W1597017789 hasRelatedWork W2148791245 @default.
• W1597017789 hasRelatedWork W2315308809 @default.
• W1597017789 hasRelatedWork W2604957457 @default.
• W1597017789 hasRelatedWork W2884937801 @default.
• W1597017789 isParatext "false" @default.
• W1597017789 isRetracted "false" @default.
• W1597017789 magId "1597017789" @default.
• W1597017789 workType "book-chapter" @default.