Matches in SemOpenAlex for { <https://semopenalex.org/work/W1597218655> ?p ?o ?g. }
- W1597218655 abstract "Demineralised white lesions (DWLs) can appear on teeth during fixed brace treatment because of early decay around the brackets that attach the braces to the teeth. Fluoride is effective in reducing decay in susceptible individuals in the general population. Individuals receiving orthodontic treatment may be prescribed various forms of fluoride treatment. This review compares the effects of various forms of fluoride used during orthodontic treatment on the development of DWLs. This is an update of a Cochrane review first published in 2004.The primary objective of this review was to evaluate the effects of fluoride in reducing the incidence of DWLs on the teeth during orthodontic treatment.The secondary objectives were to examine the effectiveness of different modes of fluoride delivery in reducing the incidence of DWLs, as well as the size of lesions. Participant-assessed outcomes, such as perception of DWLs, and oral health-related quality of life data were to be included, as would reports of adverse effects.We searched the Cochrane Oral Health Group's Trials Register (to 31 January 2013); the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 12); MEDLINE via OVID (1946 to 31 January 2013); and EMBASE via OVID (1980 to 31 January 2013).We included trials if they met the following criteria: (1) parallel-group randomised clinical trials comparing the use of a fluoride-containing product versus placebo, no treatment or a different type of fluoride treatment, in which (2) the outcome of enamel demineralisation was assessed at the start and at the end of orthodontic treatment.At least two review authors independently, in duplicate, conducted risk of bias assessments and extracted data. Authors of trials were contacted to obtain missing data or to ask for clarification of aspects of trial methodology. The Cochrane Collaboration's statistical guidelines were followed.For the 2013 update of this review, three changes were made to the protocol regarding inclusion criteria. Fourteen studies included in the previous version of the review were excluded from this update for the following reasons: five previously included studies were quasi-randomised, a further five were split-mouth studies, three measured outcomes on extracted teeth only and in one, the same fluoride intervention was used in each intervention group of the study.Three studies and 458 participants were included in this updated review. One study was assessed at low risk of bias for all domains, in one study the risk of bias was unclear and in the remaining study, the risk of bias was high.One placebo-controlled study of fluoride varnish applied every six weeks (253 participants, low risk of bias), provided moderate-quality evidence of an almost 70% reduction in DWLs (risk ratio (RR) 0.31, 95% confidence interval (CI) 0.21 to 0.44, P value < 0.001). This finding is considered to provide moderate-quality evidence for this intervention because it has not yet been replicated by further studies in orthodontic participants.One study compared two different formulations of fluoride toothpaste and mouthrinse prescribed for participants undergoing orthodontic treatment (97 participants, unclear risk of bias) and found no difference between an amine fluoride and stannous fluoride toothpaste/mouthrinse combination and a sodium fluoride toothpaste/mouthrinse combination for the outcomes of white spot index, visible plaque index and gingival bleeding index.One small study (37 participants) compared the use of an intraoral fluoride-releasing glass bead device attached to the brace versus a daily fluoride mouthrinse. The study was assessed at high risk of bias because a substantial number of participants were lost to follow-up, and compliance with use of the mouthrinse was not measured.Neither secondary outcomes of this review nor adverse effects of interventions were reported in any of the included studies.This review found some moderate evidence that fluoride varnish applied every six weeks at the time of orthodontic review during treatment is effective, but this finding is based on a single study. Further adequately powered, double-blind, randomised controlled trials are required to determine the best means of preventing DWLs in patients undergoing orthodontic treatment and the most accurate means of assessing compliance with treatment and possible adverse effects. Future studies should follow up participants beyond the end of orthodontic treatment to determine the effect of DWLs on participant satisfaction with treatment." @default.
- W1597218655 created "2016-06-24" @default.
- W1597218655 creator A5017242429 @default.
- W1597218655 creator A5027593525 @default.
- W1597218655 creator A5041511809 @default.
- W1597218655 creator A5073781351 @default.
- W1597218655 creator A5081704184 @default.
- W1597218655 creator A5089288034 @default.
- W1597218655 date "2013-12-12" @default.
- W1597218655 modified "2023-10-02" @default.
- W1597218655 title "Fluorides for the prevention of early tooth decay (demineralised white lesions) during fixed brace treatment" @default.
- W1597218655 cites W1524298720 @default.
- W1597218655 cites W1576612035 @default.
- W1597218655 cites W1596484239 @default.
- W1597218655 cites W1979641022 @default.
- W1597218655 cites W1994515393 @default.
- W1597218655 cites W1995061583 @default.
- W1597218655 cites W2010433304 @default.
- W1597218655 cites W2011275751 @default.
- W1597218655 cites W2012226420 @default.
- W1597218655 cites W2020730346 @default.
- W1597218655 cites W2021166799 @default.
- W1597218655 cites W2026575391 @default.
- W1597218655 cites W2027196362 @default.
- W1597218655 cites W2029067197 @default.
- W1597218655 cites W2031574778 @default.
- W1597218655 cites W2037316157 @default.
- W1597218655 cites W2038144878 @default.
- W1597218655 cites W2038410079 @default.
- W1597218655 cites W2040881028 @default.
- W1597218655 cites W2044384816 @default.
- W1597218655 cites W2045325466 @default.
- W1597218655 cites W2053169193 @default.
- W1597218655 cites W2058072291 @default.
- W1597218655 cites W2058677032 @default.
- W1597218655 cites W2061475589 @default.
- W1597218655 cites W2064595623 @default.
- W1597218655 cites W2067325043 @default.
- W1597218655 cites W2075462340 @default.
- W1597218655 cites W2081090137 @default.
- W1597218655 cites W2082036506 @default.
- W1597218655 cites W2085560823 @default.
- W1597218655 cites W2091386554 @default.
- W1597218655 cites W2094417710 @default.
- W1597218655 cites W2103559395 @default.
- W1597218655 cites W2110431794 @default.
- W1597218655 cites W2118293543 @default.
- W1597218655 cites W2135508699 @default.
- W1597218655 cites W2137249739 @default.
- W1597218655 cites W2139496627 @default.
- W1597218655 cites W2148508410 @default.
- W1597218655 cites W2148613458 @default.
- W1597218655 cites W2156113483 @default.
- W1597218655 cites W2157508850 @default.
- W1597218655 cites W2158832832 @default.
- W1597218655 cites W2162246583 @default.
- W1597218655 cites W2162946844 @default.
- W1597218655 cites W2164732682 @default.
- W1597218655 cites W2168092834 @default.
- W1597218655 cites W2169585550 @default.
- W1597218655 cites W2169890134 @default.
- W1597218655 cites W2317572578 @default.
- W1597218655 cites W2334820994 @default.
- W1597218655 cites W2460207201 @default.
- W1597218655 cites W2490283730 @default.
- W1597218655 cites W4251542316 @default.
- W1597218655 doi "https://doi.org/10.1002/14651858.cd003809.pub3" @default.
- W1597218655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24338792" @default.
- W1597218655 hasPublicationYear "2013" @default.
- W1597218655 type Work @default.
- W1597218655 sameAs 1597218655 @default.
- W1597218655 citedByCount "90" @default.
- W1597218655 countsByYear W15972186552014 @default.
- W1597218655 countsByYear W15972186552015 @default.
- W1597218655 countsByYear W15972186552016 @default.
- W1597218655 countsByYear W15972186552017 @default.
- W1597218655 countsByYear W15972186552018 @default.
- W1597218655 countsByYear W15972186552019 @default.
- W1597218655 countsByYear W15972186552020 @default.
- W1597218655 countsByYear W15972186552021 @default.
- W1597218655 countsByYear W15972186552022 @default.
- W1597218655 countsByYear W15972186552023 @default.
- W1597218655 crossrefType "journal-article" @default.
- W1597218655 hasAuthorship W1597218655A5017242429 @default.
- W1597218655 hasAuthorship W1597218655A5027593525 @default.
- W1597218655 hasAuthorship W1597218655A5041511809 @default.
- W1597218655 hasAuthorship W1597218655A5073781351 @default.
- W1597218655 hasAuthorship W1597218655A5081704184 @default.
- W1597218655 hasAuthorship W1597218655A5089288034 @default.
- W1597218655 hasBestOaLocation W15972186552 @default.
- W1597218655 hasConcept C120665830 @default.
- W1597218655 hasConcept C121332964 @default.
- W1597218655 hasConcept C126322002 @default.
- W1597218655 hasConcept C141071460 @default.
- W1597218655 hasConcept C142724271 @default.
- W1597218655 hasConcept C168563851 @default.
- W1597218655 hasConcept C179104552 @default.
- W1597218655 hasConcept C185592680 @default.
- W1597218655 hasConcept C197934379 @default.
- W1597218655 hasConcept C199343813 @default.