FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1597803560> ?p ?o ?g. }

• W1597803560 endingPage "3357" @default.
• W1597803560 startingPage "3340" @default.
• W1597803560 abstract "ABSTRACT Nuclei in the central nervous system are 3D aggregates of neurons that have common physiological properties, functionalities, and connectivities. To form specific nuclei, neurons migrate from their birthplace towards the presumptive nuclear region where they change their dynamics to aggregate and rearrange into a distinct 3D structure, a process that we term nucleogenesis. Nuclei, together with the laminar structure, form the basic cytoarchitectonic unit for information processing. However, in contrast to much‐studied laminar structures, the neuronal dynamics that contribute to the aggregation process to form nuclei are poorly understood. Here, we analyze nucleogenesis by observing the mouse precerebellar pontine nucleus (PN), and provide the first 4D view of nucleogenesis by tracking neuronal behaviors along the three spatial axes over time. Early‐ and late‐born PN neurons were labeled by in utero electroporation and their behaviors on cultured brain slices were recorded by time‐lapse imaging. We find that when PN neurons migrate medially into the nuclear region, many of them switch to migrate radially and laterally, to populate the dorsal and lateral PN regions, respectively. The tendency to switch to radial migration is much less in later‐born neurons, whereas that to switch to lateral migration is comparable between the two groups. In contrast to the radial and mediolateral axes, very few PN neurons switch to migrate rostrocaudally. These results could thus provide a framework for understanding the mechanisms that regulate this complex yet important process. J. Comp. Neurol. 521:3340–3357, 2013. © 2013 Wiley Periodicals, Inc." @default.
• W1597803560 created "2016-06-24" @default.
• W1597803560 creator A5029662146 @default.
• W1597803560 creator A5034372438 @default.
• W1597803560 creator A5080946962 @default.
• W1597803560 date "2013-07-25" @default.
• W1597803560 modified "2023-10-07" @default.
• W1597803560 title "Four-dimensional analysis of nucleogenesis of the pontine nucleus in the hindbrain" @default.
• W1597803560 cites W1409013807 @default.
• W1597803560 cites W1608352250 @default.
• W1597803560 cites W1967337983 @default.
• W1597803560 cites W1972798612 @default.
• W1597803560 cites W1976003935 @default.
• W1597803560 cites W1981164058 @default.
• W1597803560 cites W1981416137 @default.
• W1597803560 cites W1981588862 @default.
• W1597803560 cites W1982018651 @default.
• W1597803560 cites W1988448904 @default.
• W1597803560 cites W1989545395 @default.
• W1597803560 cites W1990418087 @default.
• W1597803560 cites W1990847799 @default.
• W1597803560 cites W2001347360 @default.
• W1597803560 cites W2003901930 @default.
• W1597803560 cites W2006742868 @default.
• W1597803560 cites W2015495293 @default.
• W1597803560 cites W2018739829 @default.
• W1597803560 cites W2022887923 @default.
• W1597803560 cites W2023015511 @default.
• W1597803560 cites W2026089486 @default.
• W1597803560 cites W2026656775 @default.
• W1597803560 cites W2030295356 @default.
• W1597803560 cites W2035724878 @default.
• W1597803560 cites W2041898487 @default.
• W1597803560 cites W2042910934 @default.
• W1597803560 cites W2048162805 @default.
• W1597803560 cites W2050041497 @default.
• W1597803560 cites W2062928655 @default.
• W1597803560 cites W2065778552 @default.
• W1597803560 cites W2065943966 @default.
• W1597803560 cites W2066479594 @default.
• W1597803560 cites W2068729649 @default.
• W1597803560 cites W2070275675 @default.
• W1597803560 cites W2072627666 @default.
• W1597803560 cites W2075846203 @default.
• W1597803560 cites W2076981337 @default.
• W1597803560 cites W2078172196 @default.
• W1597803560 cites W2079991275 @default.
• W1597803560 cites W2091856617 @default.
• W1597803560 cites W2093983408 @default.
• W1597803560 cites W2097248752 @default.
• W1597803560 cites W2101345386 @default.
• W1597803560 cites W2105764979 @default.
• W1597803560 cites W2108504850 @default.
• W1597803560 cites W2119458248 @default.
• W1597803560 cites W2131233061 @default.
• W1597803560 cites W2137566501 @default.
• W1597803560 cites W2143097535 @default.
• W1597803560 cites W2160040915 @default.
• W1597803560 cites W2166852250 @default.
• W1597803560 cites W2168553061 @default.
• W1597803560 cites W2169549562 @default.
• W1597803560 cites W2170083890 @default.
• W1597803560 cites W2170286329 @default.
• W1597803560 cites W2312569928 @default.
• W1597803560 doi "https://doi.org/10.1002/cne.23353" @default.
• W1597803560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23640820" @default.
• W1597803560 hasPublicationYear "2013" @default.
• W1597803560 type Work @default.
• W1597803560 sameAs 1597803560 @default.
• W1597803560 citedByCount "20" @default.
• W1597803560 countsByYear W15978035602014 @default.
• W1597803560 countsByYear W15978035602015 @default.
• W1597803560 countsByYear W15978035602016 @default.
• W1597803560 countsByYear W15978035602017 @default.
• W1597803560 countsByYear W15978035602018 @default.
• W1597803560 countsByYear W15978035602019 @default.
• W1597803560 countsByYear W15978035602020 @default.
• W1597803560 countsByYear W15978035602021 @default.
• W1597803560 countsByYear W15978035602022 @default.
• W1597803560 countsByYear W15978035602023 @default.
• W1597803560 crossrefType "journal-article" @default.
• W1597803560 hasAuthorship W1597803560A5029662146 @default.
• W1597803560 hasAuthorship W1597803560A5034372438 @default.
• W1597803560 hasAuthorship W1597803560A5080946962 @default.
• W1597803560 hasConcept C105702510 @default.
• W1597803560 hasConcept C111919701 @default.
• W1597803560 hasConcept C140530291 @default.
• W1597803560 hasConcept C169760540 @default.
• W1597803560 hasConcept C2777075493 @default.
• W1597803560 hasConcept C2780723820 @default.
• W1597803560 hasConcept C2781304537 @default.
• W1597803560 hasConcept C2909943617 @default.
• W1597803560 hasConcept C41008148 @default.
• W1597803560 hasConcept C529278444 @default.
• W1597803560 hasConcept C86803240 @default.
• W1597803560 hasConcept C98045186 @default.
• W1597803560 hasConceptScore W1597803560C105702510 @default.
• W1597803560 hasConceptScore W1597803560C111919701 @default.

• next