Matches in SemOpenAlex for { <https://semopenalex.org/work/W1598309312> ?p ?o ?g. }
- W1598309312 endingPage "e0133019" @default.
- W1598309312 startingPage "e0133019" @default.
- W1598309312 abstract "The aim of this study was to investigate the expression of DAX-1 in a series of pediatric rhabdomyosarcomas (RMS) with known translocation and compare it to Ap2β, known to be selectively expressed in ARMS.We revised a series of 71 alveolar rhabdomyosarcomas (ARMS), enrolled in the Italian Protocols RMS 79 and 96, and 23 embryonal rhabdomyosarcomas (ERMS) as controls. Before investigating Ap2β and DAX-1, ARMS were reviewed and reclassified as 48 ARMS and 23 non-ARMS.Translocation positive ARMS showed a characteristic Ap2β/DAX-1+ staining pattern in 78% of cases, while 76% of classic ERMS were negative for both. Ap2β alone was positive in 3.9% of RMS lacking translocation, whereas DAX-1 alone was positive in 25.4%. Conversely, 9% and 6% of translocation positive ARMS were positive only for DAX-1 or Ap2β, respectively. The 23 non-ARMS shared the same phenotype as ERMS but had a higher frequency of DAX-1 expression.DAX-1 is less specific than Ap2β, however it is a sensitive marker for translocation positive ARMS and can be helpful in their diagnosis if used in combination with Ap2β." @default.
- W1598309312 created "2016-06-24" @default.
- W1598309312 creator A5009947836 @default.
- W1598309312 creator A5015423699 @default.
- W1598309312 creator A5019871831 @default.
- W1598309312 creator A5038132511 @default.
- W1598309312 creator A5054972765 @default.
- W1598309312 creator A5061265109 @default.
- W1598309312 creator A5066632429 @default.
- W1598309312 creator A5070186540 @default.
- W1598309312 creator A5075951287 @default.
- W1598309312 creator A5084238877 @default.
- W1598309312 date "2015-07-13" @default.
- W1598309312 modified "2023-10-09" @default.
- W1598309312 title "DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma" @default.
- W1598309312 cites W1504229479 @default.
- W1598309312 cites W1558871366 @default.
- W1598309312 cites W192601499 @default.
- W1598309312 cites W1964278478 @default.
- W1598309312 cites W1971639718 @default.
- W1598309312 cites W1973606269 @default.
- W1598309312 cites W1983889411 @default.
- W1598309312 cites W1988422395 @default.
- W1598309312 cites W1989691634 @default.
- W1598309312 cites W1991167271 @default.
- W1598309312 cites W1995353076 @default.
- W1598309312 cites W1997220932 @default.
- W1598309312 cites W2004024312 @default.
- W1598309312 cites W2005239067 @default.
- W1598309312 cites W2011935366 @default.
- W1598309312 cites W2012694543 @default.
- W1598309312 cites W2018310400 @default.
- W1598309312 cites W2022560804 @default.
- W1598309312 cites W2037378466 @default.
- W1598309312 cites W2047979053 @default.
- W1598309312 cites W2048649672 @default.
- W1598309312 cites W2050320084 @default.
- W1598309312 cites W2056144743 @default.
- W1598309312 cites W2061777493 @default.
- W1598309312 cites W2063158088 @default.
- W1598309312 cites W2063583146 @default.
- W1598309312 cites W2079499141 @default.
- W1598309312 cites W2081261283 @default.
- W1598309312 cites W2087387853 @default.
- W1598309312 cites W2092724993 @default.
- W1598309312 cites W2093742476 @default.
- W1598309312 cites W2101405991 @default.
- W1598309312 cites W2102352112 @default.
- W1598309312 cites W2117335871 @default.
- W1598309312 cites W2119501563 @default.
- W1598309312 cites W2127843391 @default.
- W1598309312 cites W2170407716 @default.
- W1598309312 cites W2170709473 @default.
- W1598309312 cites W2171879013 @default.
- W1598309312 cites W2316363203 @default.
- W1598309312 cites W2416032761 @default.
- W1598309312 cites W4255972573 @default.
- W1598309312 doi "https://doi.org/10.1371/journal.pone.0133019" @default.
- W1598309312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4500404" @default.
- W1598309312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26168243" @default.
- W1598309312 hasPublicationYear "2015" @default.
- W1598309312 type Work @default.
- W1598309312 sameAs 1598309312 @default.
- W1598309312 citedByCount "0" @default.
- W1598309312 crossrefType "journal-article" @default.
- W1598309312 hasAuthorship W1598309312A5009947836 @default.
- W1598309312 hasAuthorship W1598309312A5015423699 @default.
- W1598309312 hasAuthorship W1598309312A5019871831 @default.
- W1598309312 hasAuthorship W1598309312A5038132511 @default.
- W1598309312 hasAuthorship W1598309312A5054972765 @default.
- W1598309312 hasAuthorship W1598309312A5061265109 @default.
- W1598309312 hasAuthorship W1598309312A5066632429 @default.
- W1598309312 hasAuthorship W1598309312A5070186540 @default.
- W1598309312 hasAuthorship W1598309312A5075951287 @default.
- W1598309312 hasAuthorship W1598309312A5084238877 @default.
- W1598309312 hasBestOaLocation W15983093121 @default.
- W1598309312 hasConcept C104317684 @default.
- W1598309312 hasConcept C127716648 @default.
- W1598309312 hasConcept C138626823 @default.
- W1598309312 hasConcept C142724271 @default.
- W1598309312 hasConcept C204232928 @default.
- W1598309312 hasConcept C2776522094 @default.
- W1598309312 hasConcept C2778256501 @default.
- W1598309312 hasConcept C2780844630 @default.
- W1598309312 hasConcept C502942594 @default.
- W1598309312 hasConcept C54355233 @default.
- W1598309312 hasConcept C71924100 @default.
- W1598309312 hasConcept C86803240 @default.
- W1598309312 hasConceptScore W1598309312C104317684 @default.
- W1598309312 hasConceptScore W1598309312C127716648 @default.
- W1598309312 hasConceptScore W1598309312C138626823 @default.
- W1598309312 hasConceptScore W1598309312C142724271 @default.
- W1598309312 hasConceptScore W1598309312C204232928 @default.
- W1598309312 hasConceptScore W1598309312C2776522094 @default.
- W1598309312 hasConceptScore W1598309312C2778256501 @default.
- W1598309312 hasConceptScore W1598309312C2780844630 @default.
- W1598309312 hasConceptScore W1598309312C502942594 @default.
- W1598309312 hasConceptScore W1598309312C54355233 @default.