Matches in SemOpenAlex for { <https://semopenalex.org/work/W1598494150> ?p ?o ?g. }
- W1598494150 endingPage "471" @default.
- W1598494150 startingPage "455" @default.
- W1598494150 abstract "This chapter reviews the clinical, neuroimaging, and neuropathological features of pediatric neuro-AIDS (prior to the use of antiretroviral (ARV) agents) and the changing neuroepidemiology in the highly active ARV therapy (HAART) era. Salient features of pediatric HIV/AIDS and its epidemiology are briefly summarized, since there are major differences between adult and pediatric HIV/AIDS, and neurological aspects need to be viewed in the context of this complex and progressive illness for which the epidemiology is diverse and changing, as are treatment protocols and their availabilities. Among adolescents, intravenous drug use and sexual exposure are the most common risk factors for acquiring HIV-1 infection. Some children develop progressive and disabling motor deficits yet maintain relatively stable (albeit impaired) cognitive and adaptive social skills, whereas others have more impaired cognitive than motor function. Some children can also have relatively stable minor motor and cognitive findings. Host genetic factors are relevant as well (e.g., CCR5 and CXCR4 polymorphisms, virus-host interactions affecting genes and gene products, and as-yet-undefined virus-host interactions). Secondary central nervous system (CNS) complications should be considered in the differential diagnosis of the HIV-1-infected child who presents with new onset of mental status changes, headache, seizures, or focal neurological deficits. The most effective way to prevent pediatric HIV-1-associated neurological syndromes is to prevent vertically acquired HIV-1 infection. Clearly the most effective strategy to achieve this goal is to prevent HIV-1 infection in all women of childbearing age." @default.
- W1598494150 created "2016-06-24" @default.
- W1598494150 creator A5085186797 @default.
- W1598494150 date "2014-04-09" @default.
- W1598494150 modified "2023-09-25" @default.
- W1598494150 title "Pediatric Neuro-AIDS" @default.
- W1598494150 cites W117901537 @default.
- W1598494150 cites W1267291552 @default.
- W1598494150 cites W1516480248 @default.
- W1598494150 cites W1552105690 @default.
- W1598494150 cites W1964867999 @default.
- W1598494150 cites W1966147831 @default.
- W1598494150 cites W1967299169 @default.
- W1598494150 cites W1967618107 @default.
- W1598494150 cites W1971397856 @default.
- W1598494150 cites W1971771720 @default.
- W1598494150 cites W1974457683 @default.
- W1598494150 cites W1975633434 @default.
- W1598494150 cites W1976215904 @default.
- W1598494150 cites W1976290918 @default.
- W1598494150 cites W1979490529 @default.
- W1598494150 cites W1981723477 @default.
- W1598494150 cites W1983534376 @default.
- W1598494150 cites W1987683879 @default.
- W1598494150 cites W1988922544 @default.
- W1598494150 cites W1991477935 @default.
- W1598494150 cites W1991509441 @default.
- W1598494150 cites W1992126368 @default.
- W1598494150 cites W1992320273 @default.
- W1598494150 cites W1993868432 @default.
- W1598494150 cites W1994669505 @default.
- W1598494150 cites W1999770289 @default.
- W1598494150 cites W2000450801 @default.
- W1598494150 cites W2001340574 @default.
- W1598494150 cites W2001840443 @default.
- W1598494150 cites W2002987386 @default.
- W1598494150 cites W2008520978 @default.
- W1598494150 cites W2009027407 @default.
- W1598494150 cites W2009539288 @default.
- W1598494150 cites W2009790521 @default.
- W1598494150 cites W2010431080 @default.
- W1598494150 cites W2011353921 @default.
- W1598494150 cites W2012103066 @default.
- W1598494150 cites W2014484523 @default.
- W1598494150 cites W2014795015 @default.
- W1598494150 cites W2016360383 @default.
- W1598494150 cites W2016738212 @default.
- W1598494150 cites W2018224520 @default.
- W1598494150 cites W2018265414 @default.
- W1598494150 cites W2018499708 @default.
- W1598494150 cites W2021430036 @default.
- W1598494150 cites W2023671179 @default.
- W1598494150 cites W2024199905 @default.
- W1598494150 cites W2024636722 @default.
- W1598494150 cites W2026512368 @default.
- W1598494150 cites W2032465149 @default.
- W1598494150 cites W2033619805 @default.
- W1598494150 cites W2033695552 @default.
- W1598494150 cites W2036250213 @default.
- W1598494150 cites W2038840428 @default.
- W1598494150 cites W2039954573 @default.
- W1598494150 cites W2040769397 @default.
- W1598494150 cites W2043213710 @default.
- W1598494150 cites W2044112075 @default.
- W1598494150 cites W2045100678 @default.
- W1598494150 cites W2045301606 @default.
- W1598494150 cites W2045324185 @default.
- W1598494150 cites W2045693849 @default.
- W1598494150 cites W2045960454 @default.
- W1598494150 cites W2046884729 @default.
- W1598494150 cites W2047870237 @default.
- W1598494150 cites W2049288936 @default.
- W1598494150 cites W2051812953 @default.
- W1598494150 cites W2052960263 @default.
- W1598494150 cites W2053031409 @default.
- W1598494150 cites W2053219059 @default.
- W1598494150 cites W2054980981 @default.
- W1598494150 cites W2056841715 @default.
- W1598494150 cites W2057210888 @default.
- W1598494150 cites W2057506112 @default.
- W1598494150 cites W2057769653 @default.
- W1598494150 cites W2057978574 @default.
- W1598494150 cites W2059873581 @default.
- W1598494150 cites W2060154073 @default.
- W1598494150 cites W2061549298 @default.
- W1598494150 cites W2063265842 @default.
- W1598494150 cites W2064249567 @default.
- W1598494150 cites W2064983077 @default.
- W1598494150 cites W2065323547 @default.
- W1598494150 cites W2065597046 @default.
- W1598494150 cites W2066519500 @default.
- W1598494150 cites W2068169102 @default.
- W1598494150 cites W2068884761 @default.
- W1598494150 cites W2069054708 @default.
- W1598494150 cites W2069864938 @default.
- W1598494150 cites W2070764619 @default.
- W1598494150 cites W2073078781 @default.
- W1598494150 cites W2073144616 @default.