Matches in SemOpenAlex for { <https://semopenalex.org/work/W1598515510> ?p ?o ?g. }
- W1598515510 abstract "Motor recovery after stroke involves developing new neural connections, acquiring new functions, and compensating for impairments. These processes are related to neural plasticity. Various novel stroke rehabilitation techniques based on basic science and clinical studies of neural plasticity have been developed to aid motor recovery. Current research aims to determine whether using combinations of these techniques can synergistically improve motor recovery. When different stroke neurorehabilitation therapies are combined, the timing of each therapeutic program must be considered to enable optimal neural plasticity. Synchronizing stroke rehabilitation with voluntary neural and/or muscle activity can lead to motor recovery by targeting Hebbian plasticity. This reinforces the neural connections between paretic muscles and the residual motor area. Homeostatic metaplasticity, which stabilizes the activity of neurons and neural circuits, can either augment or reduce the synergic effect depending on the timing of combination therapy and types of neurorehabilitation that are used. Moreover, the possibility that the threshold and degree of induced plasticity can be altered after stroke should be noted. This review focuses on the mechanisms underlying combinations of neurorehabilitation approaches and their future clinical applications. We suggest therapeutic approaches for cortical reorganization and maximal functional gain in patients with stroke, based on the processes of Hebbian plasticity and homeostatic metaplasticity. Few of the possible combinations of stroke neurorehabilitation have been tested experimentally; therefore, further studies are required to determine the appropriate combination for motor recovery." @default.
- W1598515510 created "2016-06-24" @default.
- W1598515510 creator A5016455883 @default.
- W1598515510 creator A5075930674 @default.
- W1598515510 date "2015-06-23" @default.
- W1598515510 modified "2023-10-10" @default.
- W1598515510 title "Combinations of stroke neurorehabilitation to facilitate motor recovery: perspectives on Hebbian plasticity and homeostatic metaplasticity" @default.
- W1598515510 cites W1484449035 @default.
- W1598515510 cites W1509799360 @default.
- W1598515510 cites W1520463686 @default.
- W1598515510 cites W1529597595 @default.
- W1598515510 cites W1543683380 @default.
- W1598515510 cites W1601528091 @default.
- W1598515510 cites W1733248925 @default.
- W1598515510 cites W1752230054 @default.
- W1598515510 cites W1774728488 @default.
- W1598515510 cites W1938199795 @default.
- W1598515510 cites W1966127376 @default.
- W1598515510 cites W1967077913 @default.
- W1598515510 cites W1967142320 @default.
- W1598515510 cites W1970879301 @default.
- W1598515510 cites W1971140534 @default.
- W1598515510 cites W1972813402 @default.
- W1598515510 cites W1973032297 @default.
- W1598515510 cites W1973311433 @default.
- W1598515510 cites W1974583652 @default.
- W1598515510 cites W1977716670 @default.
- W1598515510 cites W1977722200 @default.
- W1598515510 cites W1982336939 @default.
- W1598515510 cites W1982405461 @default.
- W1598515510 cites W1983401000 @default.
- W1598515510 cites W1985067482 @default.
- W1598515510 cites W1986012099 @default.
- W1598515510 cites W1987467672 @default.
- W1598515510 cites W1990833472 @default.
- W1598515510 cites W1991711453 @default.
- W1598515510 cites W1993349143 @default.
- W1598515510 cites W1993725941 @default.
- W1598515510 cites W1996625619 @default.
- W1598515510 cites W2005913217 @default.
- W1598515510 cites W2009782019 @default.
- W1598515510 cites W2011551368 @default.
- W1598515510 cites W2016035864 @default.
- W1598515510 cites W2016478370 @default.
- W1598515510 cites W2016855117 @default.
- W1598515510 cites W2017043857 @default.
- W1598515510 cites W2024169567 @default.
- W1598515510 cites W2024866589 @default.
- W1598515510 cites W2028805271 @default.
- W1598515510 cites W2029080804 @default.
- W1598515510 cites W2031190127 @default.
- W1598515510 cites W2032635843 @default.
- W1598515510 cites W2034753893 @default.
- W1598515510 cites W2037249140 @default.
- W1598515510 cites W2041621588 @default.
- W1598515510 cites W2042856776 @default.
- W1598515510 cites W2045005199 @default.
- W1598515510 cites W2045421141 @default.
- W1598515510 cites W2047535883 @default.
- W1598515510 cites W2049073345 @default.
- W1598515510 cites W2051609734 @default.
- W1598515510 cites W2053108936 @default.
- W1598515510 cites W2053281035 @default.
- W1598515510 cites W2056338323 @default.
- W1598515510 cites W2056881813 @default.
- W1598515510 cites W2060822129 @default.
- W1598515510 cites W2062951016 @default.
- W1598515510 cites W2063206977 @default.
- W1598515510 cites W2064181761 @default.
- W1598515510 cites W2064434028 @default.
- W1598515510 cites W2068399228 @default.
- W1598515510 cites W2072645795 @default.
- W1598515510 cites W2073227393 @default.
- W1598515510 cites W2073242124 @default.
- W1598515510 cites W2073633782 @default.
- W1598515510 cites W2074762213 @default.
- W1598515510 cites W2075019019 @default.
- W1598515510 cites W2080095333 @default.
- W1598515510 cites W2081668270 @default.
- W1598515510 cites W2085374012 @default.
- W1598515510 cites W2085440246 @default.
- W1598515510 cites W2086127604 @default.
- W1598515510 cites W2086313140 @default.
- W1598515510 cites W2087287335 @default.
- W1598515510 cites W2087874301 @default.
- W1598515510 cites W2088591659 @default.
- W1598515510 cites W2088849407 @default.
- W1598515510 cites W2091495070 @default.
- W1598515510 cites W2091823845 @default.
- W1598515510 cites W2097273459 @default.
- W1598515510 cites W2098147635 @default.
- W1598515510 cites W2098555988 @default.
- W1598515510 cites W2102555719 @default.
- W1598515510 cites W2103270219 @default.
- W1598515510 cites W2105655887 @default.
- W1598515510 cites W2107642454 @default.
- W1598515510 cites W2108025392 @default.
- W1598515510 cites W2108416046 @default.
- W1598515510 cites W2109025218 @default.
- W1598515510 cites W2112910322 @default.