FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1599629765> ?p ?o ?g. }

• W1599629765 endingPage "1008" @default.
• W1599629765 startingPage "1001" @default.
• W1599629765 abstract "Background: The aim of this study was to examine trends of clinical outcome and to clarify surrogate markers when titrating β-blocker in heart failure patients with reduced left ventricular ejection fraction (HFrEF, LVEF <50%). Methods and Results: Consecutive HFrEF patients starting on β-blocker were divided into 2 groups according to time of dose fixation attainment: before 31 December 2005 (group 1, n=108) or after 1 January 2006 (group 2, n=119). There were no significant differences in patient characteristics between the 2 groups at baseline. Beta-blocker fixed dose was higher with lower resting heart rate in group 2 (6.2±5.7mg/day vs. 9.5±9.1mg/day in carvedilol equivalent dose, P=0.001; 74.2±11.1beats/min vs. 70.2±9.7beats/min, P=0.004). The rate of HF hospitalization and/or all-cause death after 36 months was lower in group 2 than in group 1 (22% vs. 38%, P=0.011; hazard ratio, 0.90; P=0.012). Cox regression analysis showed that β-blocker ≥10mg/day and achieved heart rate ≤71beats/min predicted a better outcome (both P<0.05). Conclusions: Recent improvement of clinical outcome among HFrEF patients may be attributable to the up-titration policy accompanying lowered heart rate. Resting heart rate ≤71beats/min and β-blocker ≥10mg/day (ie, 50% of the target dose for Japanese patients) could be surrogate markers when titrating β-blocker. (Circ J 2013; 77: 1001–1008)" @default.
• W1599629765 created "2016-06-24" @default.
• W1599629765 creator A5009215615 @default.
• W1599629765 creator A5014652720 @default.
• W1599629765 creator A5023817300 @default.
• W1599629765 creator A5023839140 @default.
• W1599629765 creator A5027203076 @default.
• W1599629765 creator A5037150647 @default.
• W1599629765 creator A5038275040 @default.
• W1599629765 creator A5043431227 @default.
• W1599629765 creator A5047673060 @default.
• W1599629765 creator A5057781163 @default.
• W1599629765 creator A5065533956 @default.
• W1599629765 creator A5090899335 @default.
• W1599629765 date "2013-01-01" @default.
• W1599629765 modified "2023-09-30" @default.
• W1599629765 title "Trend of Clinical Outcome and Surrogate Markers During Titration of β-Blocker in Heart Failure Patients With Reduced Ejection Fraction" @default.
• W1599629765 cites W160522169 @default.
• W1599629765 cites W179614798 @default.
• W1599629765 cites W1970080593 @default.
• W1599629765 cites W197537298 @default.
• W1599629765 cites W1985431801 @default.
• W1599629765 cites W2021390531 @default.
• W1599629765 cites W2029524820 @default.
• W1599629765 cites W2044809688 @default.
• W1599629765 cites W2046494590 @default.
• W1599629765 cites W2046746746 @default.
• W1599629765 cites W2065841554 @default.
• W1599629765 cites W2088864613 @default.
• W1599629765 cites W2095339761 @default.
• W1599629765 cites W2119340816 @default.
• W1599629765 cites W2123495845 @default.
• W1599629765 cites W2125268034 @default.
• W1599629765 cites W2136642260 @default.
• W1599629765 cites W2137784332 @default.
• W1599629765 cites W2148910374 @default.
• W1599629765 cites W2152189242 @default.
• W1599629765 cites W2154103386 @default.
• W1599629765 cites W2154143064 @default.
• W1599629765 cites W2163134559 @default.
• W1599629765 cites W2170675714 @default.
• W1599629765 cites W2296998040 @default.
• W1599629765 cites W2326508838 @default.
• W1599629765 cites W2334887619 @default.
• W1599629765 cites W2439536247 @default.
• W1599629765 cites W40175792 @default.
• W1599629765 cites W52877415 @default.
• W1599629765 doi "https://doi.org/10.1253/circj.cj-12-1241" @default.
• W1599629765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23258250" @default.
• W1599629765 hasPublicationYear "2013" @default.
• W1599629765 type Work @default.
• W1599629765 sameAs 1599629765 @default.
• W1599629765 citedByCount "23" @default.
• W1599629765 countsByYear W15996297652013 @default.
• W1599629765 countsByYear W15996297652014 @default.
• W1599629765 countsByYear W15996297652015 @default.
• W1599629765 countsByYear W15996297652016 @default.
• W1599629765 countsByYear W15996297652017 @default.
• W1599629765 countsByYear W15996297652018 @default.
• W1599629765 countsByYear W15996297652019 @default.
• W1599629765 countsByYear W15996297652020 @default.
• W1599629765 countsByYear W15996297652021 @default.
• W1599629765 countsByYear W15996297652022 @default.
• W1599629765 countsByYear W15996297652023 @default.
• W1599629765 crossrefType "journal-article" @default.
• W1599629765 hasAuthorship W1599629765A5009215615 @default.
• W1599629765 hasAuthorship W1599629765A5014652720 @default.
• W1599629765 hasAuthorship W1599629765A5023817300 @default.
• W1599629765 hasAuthorship W1599629765A5023839140 @default.
• W1599629765 hasAuthorship W1599629765A5027203076 @default.
• W1599629765 hasAuthorship W1599629765A5037150647 @default.
• W1599629765 hasAuthorship W1599629765A5038275040 @default.
• W1599629765 hasAuthorship W1599629765A5043431227 @default.
• W1599629765 hasAuthorship W1599629765A5047673060 @default.
• W1599629765 hasAuthorship W1599629765A5057781163 @default.
• W1599629765 hasAuthorship W1599629765A5065533956 @default.
• W1599629765 hasAuthorship W1599629765A5090899335 @default.
• W1599629765 hasBestOaLocation W15996297651 @default.
• W1599629765 hasConcept C126322002 @default.
• W1599629765 hasConcept C164705383 @default.
• W1599629765 hasConcept C207103383 @default.
• W1599629765 hasConcept C2777953023 @default.
• W1599629765 hasConcept C2778198053 @default.
• W1599629765 hasConcept C2778742482 @default.
• W1599629765 hasConcept C2780591200 @default.
• W1599629765 hasConcept C44249647 @default.
• W1599629765 hasConcept C50382708 @default.
• W1599629765 hasConcept C71924100 @default.
• W1599629765 hasConcept C78085059 @default.
• W1599629765 hasConcept C84393581 @default.
• W1599629765 hasConceptScore W1599629765C126322002 @default.
• W1599629765 hasConceptScore W1599629765C164705383 @default.
• W1599629765 hasConceptScore W1599629765C207103383 @default.
• W1599629765 hasConceptScore W1599629765C2777953023 @default.
• W1599629765 hasConceptScore W1599629765C2778198053 @default.
• W1599629765 hasConceptScore W1599629765C2778742482 @default.
• W1599629765 hasConceptScore W1599629765C2780591200 @default.
• W1599629765 hasConceptScore W1599629765C44249647 @default.

• next