Matches in SemOpenAlex for { <https://semopenalex.org/work/W1599687958> ?p ?o ?g. }
- W1599687958 abstract "Infection of mice with Helicobacter hepaticus is common in research colonies, yet little is known about how this persistent infection affects immunologic research. The goal of this study was to determine whether H. hepaticus infection status can modulate immune responses specific to herpes simplex virus type 1 (HSV1) and the phenotypic and functional characteristics of dendritic cells (DC) of mice. We compared virus-specific antibody and T cell-mediated responses in H. hepaticus-infected and noninfected mice that were inoculated intranasally with HSV1. The effect of H. hepaticus on the HSV1-specific antibody and T cell-mediated immune responses in superficial cervical and tracheobronchal lymph nodes (LN) did not reach statistical significance. Surface expression of the maturation-associated markers CD40, CD80, CD86, and MHC II and percentages of IL12p40- and TNFalpha-producing DC from spleen and colic LN in H. hepaticus-infected mice and noninfected mice were measured in separate experiments. Expression of CD40, CD86, and MHC II and percentages of IL12p40- and TNFalpha-producing DC from colic LN were decreased in H. hepaticus-infected mice. In contrast, H. hepaticus infection did not reduce the expression of these molecules by splenic DC. Expression of CD40, CD80, CD86, and MHC II on splenic DC from H. hepaticus-infected mice was increased after in vitro lipopolysaccharide stimulation. These results indicate that H. hepaticus infection can influence the results of immunologic assays in mice and support the use of H. hepaticus-free mice in immunologic research." @default.
- W1599687958 created "2016-06-24" @default.
- W1599687958 creator A5035678578 @default.
- W1599687958 creator A5035916958 @default.
- W1599687958 creator A5043198421 @default.
- W1599687958 creator A5091210709 @default.
- W1599687958 date "2009-12-01" @default.
- W1599687958 modified "2023-10-01" @default.
- W1599687958 title "The effect of Helicobacter hepaticus infection on immune responses specific to herpes simplex virus type 1 and characteristics of dendritic cells." @default.
- W1599687958 cites W1570367374 @default.
- W1599687958 cites W1675758671 @default.
- W1599687958 cites W1822840505 @default.
- W1599687958 cites W1854135871 @default.
- W1599687958 cites W193394063 @default.
- W1599687958 cites W1967092720 @default.
- W1599687958 cites W1977391544 @default.
- W1599687958 cites W1984239338 @default.
- W1599687958 cites W1984915215 @default.
- W1599687958 cites W1989268226 @default.
- W1599687958 cites W1993114466 @default.
- W1599687958 cites W1996291400 @default.
- W1599687958 cites W2001421303 @default.
- W1599687958 cites W2010253580 @default.
- W1599687958 cites W2033787149 @default.
- W1599687958 cites W2039263693 @default.
- W1599687958 cites W2045681339 @default.
- W1599687958 cites W2066761700 @default.
- W1599687958 cites W2085540113 @default.
- W1599687958 cites W2088255407 @default.
- W1599687958 cites W2106925029 @default.
- W1599687958 cites W2111544074 @default.
- W1599687958 cites W2115157675 @default.
- W1599687958 cites W2122014875 @default.
- W1599687958 cites W2124422905 @default.
- W1599687958 cites W2124521024 @default.
- W1599687958 cites W2124592218 @default.
- W1599687958 cites W2143266281 @default.
- W1599687958 cites W2148455779 @default.
- W1599687958 cites W2152808619 @default.
- W1599687958 cites W2153745966 @default.
- W1599687958 cites W2157253058 @default.
- W1599687958 cites W2157735062 @default.
- W1599687958 cites W2159575599 @default.
- W1599687958 cites W2168717997 @default.
- W1599687958 cites W2170349437 @default.
- W1599687958 cites W66567798 @default.
- W1599687958 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2798839" @default.
- W1599687958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20034428" @default.
- W1599687958 hasPublicationYear "2009" @default.
- W1599687958 type Work @default.
- W1599687958 sameAs 1599687958 @default.
- W1599687958 citedByCount "1" @default.
- W1599687958 crossrefType "journal-article" @default.
- W1599687958 hasAuthorship W1599687958A5035678578 @default.
- W1599687958 hasAuthorship W1599687958A5035916958 @default.
- W1599687958 hasAuthorship W1599687958A5043198421 @default.
- W1599687958 hasAuthorship W1599687958A5091210709 @default.
- W1599687958 hasConcept C154317977 @default.
- W1599687958 hasConcept C159047783 @default.
- W1599687958 hasConcept C159654299 @default.
- W1599687958 hasConcept C202751555 @default.
- W1599687958 hasConcept C203014093 @default.
- W1599687958 hasConcept C2522874641 @default.
- W1599687958 hasConcept C2776090121 @default.
- W1599687958 hasConcept C2776409635 @default.
- W1599687958 hasConcept C2778297628 @default.
- W1599687958 hasConcept C2780832600 @default.
- W1599687958 hasConcept C2780931953 @default.
- W1599687958 hasConcept C2781101188 @default.
- W1599687958 hasConcept C2781196997 @default.
- W1599687958 hasConcept C39347974 @default.
- W1599687958 hasConcept C54355233 @default.
- W1599687958 hasConcept C55493867 @default.
- W1599687958 hasConcept C86803240 @default.
- W1599687958 hasConcept C8891405 @default.
- W1599687958 hasConceptScore W1599687958C154317977 @default.
- W1599687958 hasConceptScore W1599687958C159047783 @default.
- W1599687958 hasConceptScore W1599687958C159654299 @default.
- W1599687958 hasConceptScore W1599687958C202751555 @default.
- W1599687958 hasConceptScore W1599687958C203014093 @default.
- W1599687958 hasConceptScore W1599687958C2522874641 @default.
- W1599687958 hasConceptScore W1599687958C2776090121 @default.
- W1599687958 hasConceptScore W1599687958C2776409635 @default.
- W1599687958 hasConceptScore W1599687958C2778297628 @default.
- W1599687958 hasConceptScore W1599687958C2780832600 @default.
- W1599687958 hasConceptScore W1599687958C2780931953 @default.
- W1599687958 hasConceptScore W1599687958C2781101188 @default.
- W1599687958 hasConceptScore W1599687958C2781196997 @default.
- W1599687958 hasConceptScore W1599687958C39347974 @default.
- W1599687958 hasConceptScore W1599687958C54355233 @default.
- W1599687958 hasConceptScore W1599687958C55493867 @default.
- W1599687958 hasConceptScore W1599687958C86803240 @default.
- W1599687958 hasConceptScore W1599687958C8891405 @default.
- W1599687958 hasLocation W15996879581 @default.
- W1599687958 hasOpenAccess W1599687958 @default.
- W1599687958 hasPrimaryLocation W15996879581 @default.
- W1599687958 hasRelatedWork W1260970261 @default.
- W1599687958 hasRelatedWork W1486831857 @default.
- W1599687958 hasRelatedWork W2002303891 @default.
- W1599687958 hasRelatedWork W2045445539 @default.