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• W1599814620 startingPage "807" @default.
• W1599814620 abstract "1.1. Twelve cases are recorded that pertain to the Zollinger-Ellison syndrome. 2.2. Five patients (cases I,II,IV,V, and VIII) had a non-beta islet cell adenoma, carcinoma, or hyperplasia of the pancreas associated with peptic ulcers. 3.3. One patient (case VI) had severe ulcer diathesis and although the Zollinger-Ellison syndrome was strongly suspected, a non-beta islet cell tumor of the pancreas was not found at autopsy after the patient died of a perforated jejunal ulcer. The remainder of the endocrine glands were also normal. It is possible that the patient had hyperplasia of the islets. 4.4. Two patients (cases III and IX) had a nonbeta islet cell tumor of the pancreas associated with hyperparathyroidism and duodenal and marginal ulcers. 5.5. One patient (case VII) had adrenal cortical hyperfunction and hyperplasia associated with a duodenal ulcer and marginal ulcers. Marginal ulcers healed after bilateral adrenalectomy. 6.6. One patient (case XI) had duodenal ulcers, a pituitary tumor, and hyperparathyroidism associated with hypothyroidism and hypoadrenalism. The ulcers healed after a parathyroid adenoma was excised. 7.7. One patient (case X) was included who had long and severe ulcer diathesis before and after adequate surgical therapy for peptic ulcer. After a duodenal carcinoid was excised, the marginal ulcers promptly healed. 8.8. One patient (case XII) had severe ulcer diathesis and was cured only after total gastrectomy. The pancreas and the remainder of his endocrine glands were normal." @default.
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• W1599814620 date "1966-12-01" @default.
• W1599814620 modified "2023-09-26" @default.
• W1599814620 title "Zollinger-ellison syndrome with interesting variations" @default.
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• W1599814620 doi "https://doi.org/10.1016/0002-9610(66)90130-9" @default.
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