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• W1599952788 abstract "A cDNA encoding the growth hormone (GH) receptor was cloned from rat liver. Both the nucleotide and translated amino acid sequence share greater than 70% similarity with the GH receptors from rabbit and human. An RNA probe was generated from this sequence for use in a solution hybridization assay to quantitate GH receptor mRNA expression in rat tissues. Expression was detected in 9/12 tissues examined, with the highest levels observed in the liver. Expression in liver, kidney, heart and muscle was developmentally regulated, being low at birth and rising to adult levels in 5 weeks. No difference was observed between hepatic expression in males and females, although livers from pregnant rats had elevated levels. Hypophysectomy and GH treatment did not affect hepatic GH receptor mRNA levels." @default.
• W1599952788 created "2016-06-24" @default.
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• W1599952788 date "1989-06-01" @default.
• W1599952788 modified "2023-10-15" @default.
• W1599952788 title "Regulation of rat growth hormone receptor gene expression" @default.
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• W1599952788 doi "https://doi.org/10.1016/s0021-9258(18)81745-8" @default.
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