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• W1600198273 abstract "This chapter reviews the dynamic changes in the organization and function of the cytoskeletal components during early zebrafish embryogenesis. It focuses on actin microfilaments in egg and zygote and microtubules during cleavage stages and gastrulation. Gastrulation involves a set of stereotyped cellular rearrangements including epiboly, involution/ingression, and convergent extension. These concurrent morphogenetic processes create the three-germ-layer organization of the embryo, place tissues, and organ rudiments in the proper position for further inductive interactions and development, and are the major forces underlying the change in the embryonic shape. Although the entire spectrum of morphogenetic cellular behaviors involved in vertebrate embryogenesis is still not known, directed cell migration, cell shape changes, cell intercalation, and oriented cell divisions are important components. In other systems, both intracellular morphogenetic processes and cellular morphogenetic behaviors employ cytoskeletal systems of microfilaments, microtubules, and intermediate filament. The chapter also reviews the first experiments analyzing cytoskeletal dynamics within cells of living zebrafish embryos. It surveys available methods for staining actin filaments and microtubules in fixed material, and provides an overview of drug and physical treatments interfering with different cytoskeletal functions during embryogenesis." @default.
• W1600198273 created "2016-06-24" @default.
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• W1600198273 date "1998-01-01" @default.
• W1600198273 modified "2023-09-24" @default.
• W1600198273 title "Chapter 12 Cytoskeletal Dynamics of the Zebrafish Embryo" @default.
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• W1600198273 doi "https://doi.org/10.1016/s0091-679x(08)61827-0" @default.
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