FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1600228347> ?p ?o ?g. }

• W1600228347 endingPage "52" @default.
• W1600228347 startingPage "2143" @default.
• W1600228347 abstract "Both melanocytes and glial cells are derived embryologically from the neural ectoderm. Their malignant transformed counterparts, melanoma and glioma cells, respectively, may share common antigens. Numerous tumor-associated antigens have been identified in melanomas but only a few a gliomas. Using an established reverse transcriptase polymerase chain reaction plus Southern blot assay, we compared the mRNA expression of melanoma-associated antigens (MAAs) of melanomas to brain tumors primarily derived from glial cells. The MAAs studied included tyrosinase (Tyr), tyrosinase-related protein-1 and -2 (TRP-1 and TRP-2), gp100, human melanoma antigen-encoding genes 1 and 3 (MAGE-1 and MAGE-3), and melanotransferrin (p97). Glioblastoma multiforme (n = 21), anaplastic astrocytoma (n = 3), ependymoma (n = 2), meningioma (n = 3), oligodendroglioma (n = 1), and melanoma (n = 12) tumor specimens were assayed for MAA mRNA expression. Glioblastoma multiforme, astrocytoma, and melanoma cell lines were also assayed. We observed that individual MAA mRNAs were expressed in these brain tumors and cell lines at varying frequencies. The melanogenesis-pathway-related MAAs Tyr, TRP-1, TRP-2, and gp100 mRNAs were also expressed at different levels in normal brain tissues but at a much lower frequency than in glioblastoma multiforme and melanoma. MAGE-1 and MAGE-3 mRNA were expressed in different types of tumor specimens and cell lines but never in normal brain tissue. Tumor antigen p97 was expressed in all types of tumors and also in normal brain tissues. These studies demonstrate that melanomas and primary brain tumors express common MAAs and could be exploited in patients with malignant glioma by active specific immunotherapy against these common MAAs." @default.
• W1600228347 created "2016-06-24" @default.
• W1600228347 creator A5000113684 @default.
• W1600228347 creator A5019844740 @default.
• W1600228347 creator A5029428307 @default.
• W1600228347 creator A5032684269 @default.
• W1600228347 creator A5055979372 @default.
• W1600228347 creator A5059506587 @default.
• W1600228347 creator A5061669049 @default.
• W1600228347 creator A5078330179 @default.
• W1600228347 date "1997-06-01" @default.
• W1600228347 modified "2023-09-27" @default.
• W1600228347 title "Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas." @default.
• W1600228347 cites W1503004495 @default.
• W1600228347 cites W1553324186 @default.
• W1600228347 cites W1561319331 @default.
• W1600228347 cites W169111141 @default.
• W1600228347 cites W1748734394 @default.
• W1600228347 cites W1851819680 @default.
• W1600228347 cites W1953419682 @default.
• W1600228347 cites W1969722889 @default.
• W1600228347 cites W1969785480 @default.
• W1600228347 cites W1973066594 @default.
• W1600228347 cites W1977273255 @default.
• W1600228347 cites W1983230977 @default.
• W1600228347 cites W1983378123 @default.
• W1600228347 cites W1985782120 @default.
• W1600228347 cites W1991952914 @default.
• W1600228347 cites W1995444172 @default.
• W1600228347 cites W2002666984 @default.
• W1600228347 cites W2006987944 @default.
• W1600228347 cites W2007872707 @default.
• W1600228347 cites W2008254883 @default.
• W1600228347 cites W2015082233 @default.
• W1600228347 cites W2025851036 @default.
• W1600228347 cites W2026599056 @default.
• W1600228347 cites W2034385129 @default.
• W1600228347 cites W2051311496 @default.
• W1600228347 cites W2062819255 @default.
• W1600228347 cites W2070242217 @default.
• W1600228347 cites W2073024206 @default.
• W1600228347 cites W2078972442 @default.
• W1600228347 cites W2081059129 @default.
• W1600228347 cites W2081774451 @default.
• W1600228347 cites W2082491032 @default.
• W1600228347 cites W2088541521 @default.
• W1600228347 cites W2097589013 @default.
• W1600228347 cites W2106227101 @default.
• W1600228347 cites W2108562020 @default.
• W1600228347 cites W2111486528 @default.
• W1600228347 cites W2115059815 @default.
• W1600228347 cites W2132671557 @default.
• W1600228347 cites W2161343890 @default.
• W1600228347 cites W2165367433 @default.
• W1600228347 cites W2288480622 @default.
• W1600228347 cites W4290294433 @default.
• W1600228347 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1858329" @default.
• W1600228347 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9176405" @default.
• W1600228347 hasPublicationYear "1997" @default.
• W1600228347 type Work @default.
• W1600228347 sameAs 1600228347 @default.
• W1600228347 citedByCount "50" @default.
• W1600228347 countsByYear W16002283472012 @default.
• W1600228347 countsByYear W16002283472013 @default.
• W1600228347 countsByYear W16002283472014 @default.
• W1600228347 countsByYear W16002283472015 @default.
• W1600228347 countsByYear W16002283472018 @default.
• W1600228347 countsByYear W16002283472021 @default.
• W1600228347 countsByYear W16002283472022 @default.
• W1600228347 countsByYear W16002283472023 @default.
• W1600228347 crossrefType "journal-article" @default.
• W1600228347 hasAuthorship W1600228347A5000113684 @default.
• W1600228347 hasAuthorship W1600228347A5019844740 @default.
• W1600228347 hasAuthorship W1600228347A5029428307 @default.
• W1600228347 hasAuthorship W1600228347A5032684269 @default.
• W1600228347 hasAuthorship W1600228347A5055979372 @default.
• W1600228347 hasAuthorship W1600228347A5059506587 @default.
• W1600228347 hasAuthorship W1600228347A5061669049 @default.
• W1600228347 hasAuthorship W1600228347A5078330179 @default.
• W1600228347 hasConcept C142724271 @default.
• W1600228347 hasConcept C147483822 @default.
• W1600228347 hasConcept C153911025 @default.
• W1600228347 hasConcept C203014093 @default.
• W1600228347 hasConcept C2776662205 @default.
• W1600228347 hasConcept C2777658100 @default.
• W1600228347 hasConcept C2777701055 @default.
• W1600228347 hasConcept C2777931997 @default.
• W1600228347 hasConcept C2778227246 @default.
• W1600228347 hasConcept C2778880634 @default.
• W1600228347 hasConcept C2779083369 @default.
• W1600228347 hasConcept C2779130545 @default.
• W1600228347 hasConcept C502942594 @default.
• W1600228347 hasConcept C71924100 @default.
• W1600228347 hasConcept C86803240 @default.
• W1600228347 hasConcept C8891405 @default.
• W1600228347 hasConceptScore W1600228347C142724271 @default.
• W1600228347 hasConceptScore W1600228347C147483822 @default.
• W1600228347 hasConceptScore W1600228347C153911025 @default.

• next