FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1600514788> ?p ?o ?g. }

• W1600514788 endingPage "330" @default.
• W1600514788 startingPage "317" @default.
• W1600514788 abstract "This chapter discusses the use of N-terminal fatty acylation sequences for targeting chimeric proteins to the plasma membrane.. The fatty acids myristate and palmitate are covalently linked to a wide variety of viral and cellular proteins. Sequence motifs located at the N terminus are responsible for conferring N-myristoylation of all known N-myristoylated proteins. In addition, signals for protein palmitoylation are often located at or near the N terminus. Many myristoylated proteins and nearly all dually fatty acylated proteins are attached to the inner leaflet of the cell plasma membrane. The N-terminal sequence motifs that direct fatty acylation have been shown to be both necessary and sufficient for conferring plasma membrane association. In addition to providing plasma membrane binding, palmitoylated sequences have been shown to confer targeting of proteins to specific plasma membrane microdomains The chapter describes the three general types of N-terminal fatty acylation motifs that are known to confer membrane binding. Type 1 motifs contain a “myristate plus basic” signal. These proteins are modified by covalent attachment of the 1Ccarbon fatty acid myristate to the N-terminal glycine residue. On the other hand, Type 2 and 3 N-terminal motifs are useful for conferring plasma membrane microdomain localization to proteins." @default.
• W1600514788 created "2016-06-24" @default.
• W1600514788 creator A5027044141 @default.
• W1600514788 creator A5040192033 @default.
• W1600514788 date "2000-01-01" @default.
• W1600514788 modified "2023-10-14" @default.
• W1600514788 title "Targeting proteins to plasma membrane and membrane microdomains by N-terminal myristoylation and palmitoylation" @default.
• W1600514788 cites W1493048369 @default.
• W1600514788 cites W1509948560 @default.
• W1600514788 cites W1512968077 @default.
• W1600514788 cites W1513667798 @default.
• W1600514788 cites W1579191879 @default.
• W1600514788 cites W1848923750 @default.
• W1600514788 cites W1919445666 @default.
• W1600514788 cites W1971803548 @default.
• W1600514788 cites W1992910677 @default.
• W1600514788 cites W2007312416 @default.
• W1600514788 cites W2022467870 @default.
• W1600514788 cites W2025409698 @default.
• W1600514788 cites W2032582749 @default.
• W1600514788 cites W2052799365 @default.
• W1600514788 cites W2060343311 @default.
• W1600514788 cites W2070660207 @default.
• W1600514788 cites W2072241649 @default.
• W1600514788 cites W2090429239 @default.
• W1600514788 cites W2093253631 @default.
• W1600514788 cites W2102965972 @default.
• W1600514788 cites W2103201163 @default.
• W1600514788 cites W2104901736 @default.
• W1600514788 cites W2106230884 @default.
• W1600514788 cites W2152186846 @default.
• W1600514788 cites W2169803769 @default.
• W1600514788 cites W95054676 @default.
• W1600514788 doi "https://doi.org/10.1016/s0076-6879(00)27287-x" @default.
• W1600514788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11044994" @default.
• W1600514788 hasPublicationYear "2000" @default.
• W1600514788 type Work @default.
• W1600514788 sameAs 1600514788 @default.
• W1600514788 citedByCount "24" @default.
• W1600514788 countsByYear W16005147882012 @default.
• W1600514788 countsByYear W16005147882013 @default.
• W1600514788 countsByYear W16005147882016 @default.
• W1600514788 countsByYear W16005147882017 @default.
• W1600514788 countsByYear W16005147882018 @default.
• W1600514788 countsByYear W16005147882020 @default.
• W1600514788 countsByYear W16005147882022 @default.
• W1600514788 crossrefType "book-chapter" @default.
• W1600514788 hasAuthorship W1600514788A5027044141 @default.
• W1600514788 hasAuthorship W1600514788A5040192033 @default.
• W1600514788 hasConcept C104317684 @default.
• W1600514788 hasConcept C14053116 @default.
• W1600514788 hasConcept C144647389 @default.
• W1600514788 hasConcept C146727910 @default.
• W1600514788 hasConcept C161200384 @default.
• W1600514788 hasConcept C167625842 @default.
• W1600514788 hasConcept C181199279 @default.
• W1600514788 hasConcept C185592680 @default.
• W1600514788 hasConcept C190283241 @default.
• W1600514788 hasConcept C193469717 @default.
• W1600514788 hasConcept C200342125 @default.
• W1600514788 hasConcept C203522944 @default.
• W1600514788 hasConcept C2778483698 @default.
• W1600514788 hasConcept C2779201268 @default.
• W1600514788 hasConcept C2779936771 @default.
• W1600514788 hasConcept C41625074 @default.
• W1600514788 hasConcept C543025807 @default.
• W1600514788 hasConcept C55493867 @default.
• W1600514788 hasConcept C560191 @default.
• W1600514788 hasConcept C57790582 @default.
• W1600514788 hasConcept C77207865 @default.
• W1600514788 hasConcept C86803240 @default.
• W1600514788 hasConcept C95444343 @default.
• W1600514788 hasConceptScore W1600514788C104317684 @default.
• W1600514788 hasConceptScore W1600514788C14053116 @default.
• W1600514788 hasConceptScore W1600514788C144647389 @default.
• W1600514788 hasConceptScore W1600514788C146727910 @default.
• W1600514788 hasConceptScore W1600514788C161200384 @default.
• W1600514788 hasConceptScore W1600514788C167625842 @default.
• W1600514788 hasConceptScore W1600514788C181199279 @default.
• W1600514788 hasConceptScore W1600514788C185592680 @default.
• W1600514788 hasConceptScore W1600514788C190283241 @default.
• W1600514788 hasConceptScore W1600514788C193469717 @default.
• W1600514788 hasConceptScore W1600514788C200342125 @default.
• W1600514788 hasConceptScore W1600514788C203522944 @default.
• W1600514788 hasConceptScore W1600514788C2778483698 @default.
• W1600514788 hasConceptScore W1600514788C2779201268 @default.
• W1600514788 hasConceptScore W1600514788C2779936771 @default.
• W1600514788 hasConceptScore W1600514788C41625074 @default.
• W1600514788 hasConceptScore W1600514788C543025807 @default.
• W1600514788 hasConceptScore W1600514788C55493867 @default.
• W1600514788 hasConceptScore W1600514788C560191 @default.
• W1600514788 hasConceptScore W1600514788C57790582 @default.
• W1600514788 hasConceptScore W1600514788C77207865 @default.
• W1600514788 hasConceptScore W1600514788C86803240 @default.
• W1600514788 hasConceptScore W1600514788C95444343 @default.
• W1600514788 hasLocation W16005147881 @default.
• W1600514788 hasLocation W16005147882 @default.
• W1600514788 hasOpenAccess W1600514788 @default.

• next