Matches in SemOpenAlex for { <https://semopenalex.org/work/W1600701683> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1600701683 endingPage "15667" @default.
- W1600701683 startingPage "15662" @default.
- W1600701683 abstract "Low density lipoprotein (LDL) inhibits phagocytosis of certain negatively charged particulates and also inhibits subsequent cellular secretory and oxidative responses to these particulates. In the present work, we have defined the structural features of LDL involved in this activity. Starch-heptane extraction depleted greater than 95% of neutral lipids but had little effect on the capacity of LDL to inhibit monosodium urate crystal- or polystyrene latex bead-induced neutrophil chemiluminescence (CL). Liposomes containing gamma-palmitoyl-beta-oleoylphosphatidylcholine (PC) with unesterified cholesterol (PC:cholesterol = 2:1), PC and sphingomyelin (PC:sphingomyelin = 2.3:1), or PC alone lacked the capacity to inhibit urate-induced CL. However, incorporation of apoB-100 into liposomes via cholate dialysis rendered them nearly as inhibitory for urate-induced neutrophil CL as LDL on a protein weight basis. Moreover, delipidated apoB-100, containing less than 3% residual phospholipid, inhibited neutrophil responses to urate crystals or latex beads (degranulation and superoxide anion release) in a stimulus-specific manner. Modifications of the lysine residues of apoB (e.g. acetylation) reduced both the capacity of LDL to inhibit urate crystal-induced CL and to bind to urate crystals. The effects of apoB lysine residue modification were reversible, proportional to the extent of modification, and were not attributable to alteration of the net charge of apoB. Thus, the apoB-100 of LDL both mediates and shares the capacity of native LDL to inhibit certain neutrophil responses to particulates." @default.
- W1600701683 created "2016-06-24" @default.
- W1600701683 creator A5013807783 @default.
- W1600701683 creator A5032907445 @default.
- W1600701683 creator A5058544739 @default.
- W1600701683 creator A5079824415 @default.
- W1600701683 date "1986-11-01" @default.
- W1600701683 modified "2023-10-18" @default.
- W1600701683 title "Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates." @default.
- W1600701683 cites W14380143 @default.
- W1600701683 cites W1487164341 @default.
- W1600701683 cites W1541077609 @default.
- W1600701683 cites W1558242213 @default.
- W1600701683 cites W1678778738 @default.
- W1600701683 cites W1893943578 @default.
- W1600701683 cites W1920171370 @default.
- W1600701683 cites W1992522249 @default.
- W1600701683 cites W1996516841 @default.
- W1600701683 cites W2003709444 @default.
- W1600701683 cites W2004845347 @default.
- W1600701683 cites W2009119064 @default.
- W1600701683 cites W2012413789 @default.
- W1600701683 cites W2018122457 @default.
- W1600701683 cites W2019683392 @default.
- W1600701683 cites W2026225698 @default.
- W1600701683 cites W2031423487 @default.
- W1600701683 cites W2043628164 @default.
- W1600701683 cites W2046147161 @default.
- W1600701683 cites W2051253059 @default.
- W1600701683 cites W2075924580 @default.
- W1600701683 cites W2079013458 @default.
- W1600701683 cites W2080904568 @default.
- W1600701683 cites W2089993857 @default.
- W1600701683 cites W2120626817 @default.
- W1600701683 cites W2138027393 @default.
- W1600701683 cites W2144536315 @default.
- W1600701683 cites W2144718273 @default.
- W1600701683 cites W2165482355 @default.
- W1600701683 cites W2398093727 @default.
- W1600701683 cites W4313313410 @default.
- W1600701683 doi "https://doi.org/10.1016/s0021-9258(18)66768-7" @default.
- W1600701683 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3096995" @default.
- W1600701683 hasPublicationYear "1986" @default.
- W1600701683 type Work @default.
- W1600701683 sameAs 1600701683 @default.
- W1600701683 citedByCount "21" @default.
- W1600701683 countsByYear W16007016832012 @default.
- W1600701683 countsByYear W16007016832013 @default.
- W1600701683 countsByYear W16007016832015 @default.
- W1600701683 countsByYear W16007016832016 @default.
- W1600701683 countsByYear W16007016832018 @default.
- W1600701683 countsByYear W16007016832019 @default.
- W1600701683 countsByYear W16007016832021 @default.
- W1600701683 crossrefType "journal-article" @default.
- W1600701683 hasAuthorship W1600701683A5013807783 @default.
- W1600701683 hasAuthorship W1600701683A5032907445 @default.
- W1600701683 hasAuthorship W1600701683A5058544739 @default.
- W1600701683 hasAuthorship W1600701683A5079824415 @default.
- W1600701683 hasBestOaLocation W16007016831 @default.
- W1600701683 hasConcept C126322002 @default.
- W1600701683 hasConcept C178790620 @default.
- W1600701683 hasConcept C185592680 @default.
- W1600701683 hasConcept C24245907 @default.
- W1600701683 hasConcept C24998067 @default.
- W1600701683 hasConcept C2778163477 @default.
- W1600701683 hasConcept C2780072125 @default.
- W1600701683 hasConcept C55493867 @default.
- W1600701683 hasConcept C62746215 @default.
- W1600701683 hasConcept C71924100 @default.
- W1600701683 hasConceptScore W1600701683C126322002 @default.
- W1600701683 hasConceptScore W1600701683C178790620 @default.
- W1600701683 hasConceptScore W1600701683C185592680 @default.
- W1600701683 hasConceptScore W1600701683C24245907 @default.
- W1600701683 hasConceptScore W1600701683C24998067 @default.
- W1600701683 hasConceptScore W1600701683C2778163477 @default.
- W1600701683 hasConceptScore W1600701683C2780072125 @default.
- W1600701683 hasConceptScore W1600701683C55493867 @default.
- W1600701683 hasConceptScore W1600701683C62746215 @default.
- W1600701683 hasConceptScore W1600701683C71924100 @default.
- W1600701683 hasIssue "33" @default.
- W1600701683 hasLocation W16007016831 @default.
- W1600701683 hasOpenAccess W1600701683 @default.
- W1600701683 hasPrimaryLocation W16007016831 @default.
- W1600701683 hasRelatedWork W123759218 @default.
- W1600701683 hasRelatedWork W1980266135 @default.
- W1600701683 hasRelatedWork W2017524567 @default.
- W1600701683 hasRelatedWork W2074076855 @default.
- W1600701683 hasRelatedWork W2084628138 @default.
- W1600701683 hasRelatedWork W2085228415 @default.
- W1600701683 hasRelatedWork W2125541816 @default.
- W1600701683 hasRelatedWork W2570447 @default.
- W1600701683 hasRelatedWork W2901608492 @default.
- W1600701683 hasRelatedWork W4253281463 @default.
- W1600701683 hasVolume "261" @default.
- W1600701683 isParatext "false" @default.
- W1600701683 isRetracted "false" @default.
- W1600701683 magId "1600701683" @default.
- W1600701683 workType "article" @default.