FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1600721449> ?p ?o ?g. }

• W1600721449 abstract "This study examines the independent and interactive effects of family history scores (FHxS) for the prevalence of ischemic heart disease with plasma lipids and subsequent morbidity and mortality from ischemic heart disease. FHxS were calculated for 514 sets of middle aged male twins who participated in the entry examination of the NHLBI Veteran twin study in 1969-1973. Comparison of the FHxS with the level of plasma total cholesterol and HDL cholesterol (HDLc) paralleled earlier reported findings in young adults; individuals with high total cholesterol in two exams 8-12 years apart had significantly (P less than .01) higher FHxS. The same relationship was noted when using the mean twin-pair cholesterol level at the initial exam when the twins were in their 40s. Using the pair means over two exams as the cotwins aged into their 50s, the association of FHxS with total cholesterol declined and pairs with HDLc persistently in the highest quintile at both exams had significantly (P less than .01) lower FHxS. The changes in the pattern of association of lipid fractions with FHxS with age parallel the reported age decline of total cholesterol as a risk factor for heart disease. Assessment of ischemic heart disease events up to January 1988 revealed a highly significant association (P less than .0001) of later ischemic heart disease events with FHxS. At each level of lipid categorization pairs who later had events had higher FHxS than those without any subsequent heart disease; these differences were significant in all but the low risk lipid groups (low total cholesterol, high HDLc, and low total cholesterol/HDLc ratio). We conclude that FHxS is related to total cholesterol and HDLc but also is an independent predictor of subsequent ischemic heart disease after 14-18 years of follow-up." @default.
• W1600721449 created "2016-06-24" @default.
• W1600721449 creator A5043746768 @default.
• W1600721449 creator A5057050252 @default.
• W1600721449 creator A5071319129 @default.
• W1600721449 date "1990-01-01" @default.
• W1600721449 modified "2023-09-23" @default.
• W1600721449 title "Family history of ischemic heart disease with respect to mean twin-pair cholesterol and subsequent ischemic heart disease in the NHLBI twin study" @default.
• W1600721449 cites W1978569720 @default.
• W1600721449 cites W1978655942 @default.
• W1600721449 cites W1987997851 @default.
• W1600721449 cites W1999794740 @default.
• W1600721449 cites W2017354877 @default.
• W1600721449 cites W2025452032 @default.
• W1600721449 cites W2034452039 @default.
• W1600721449 cites W2094768566 @default.
• W1600721449 cites W2103603150 @default.
• W1600721449 cites W2111938986 @default.
• W1600721449 cites W2134662886 @default.
• W1600721449 cites W2339453015 @default.
• W1600721449 cites W2339616051 @default.
• W1600721449 cites W2424256750 @default.
• W1600721449 cites W4296976561 @default.
• W1600721449 doi "https://doi.org/10.1002/gepi.1370070504" @default.
• W1600721449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2253868" @default.
• W1600721449 hasPublicationYear "1990" @default.
• W1600721449 type Work @default.
• W1600721449 sameAs 1600721449 @default.
• W1600721449 citedByCount "5" @default.
• W1600721449 crossrefType "journal-article" @default.
• W1600721449 hasAuthorship W1600721449A5043746768 @default.
• W1600721449 hasAuthorship W1600721449A5057050252 @default.
• W1600721449 hasAuthorship W1600721449A5071319129 @default.
• W1600721449 hasConcept C126322002 @default.
• W1600721449 hasConcept C164705383 @default.
• W1600721449 hasConcept C2778163477 @default.
• W1600721449 hasConcept C2779134260 @default.
• W1600721449 hasConcept C2780074459 @default.
• W1600721449 hasConcept C2781179581 @default.
• W1600721449 hasConcept C42407357 @default.
• W1600721449 hasConcept C50440223 @default.
• W1600721449 hasConcept C71924100 @default.
• W1600721449 hasConceptScore W1600721449C126322002 @default.
• W1600721449 hasConceptScore W1600721449C164705383 @default.
• W1600721449 hasConceptScore W1600721449C2778163477 @default.
• W1600721449 hasConceptScore W1600721449C2779134260 @default.
• W1600721449 hasConceptScore W1600721449C2780074459 @default.
• W1600721449 hasConceptScore W1600721449C2781179581 @default.
• W1600721449 hasConceptScore W1600721449C42407357 @default.
• W1600721449 hasConceptScore W1600721449C50440223 @default.
• W1600721449 hasConceptScore W1600721449C71924100 @default.
• W1600721449 hasLocation W16007214491 @default.
• W1600721449 hasLocation W16007214492 @default.
• W1600721449 hasOpenAccess W1600721449 @default.
• W1600721449 hasPrimaryLocation W16007214491 @default.
• W1600721449 hasRelatedWork W1964399778 @default.
• W1600721449 hasRelatedWork W1988035319 @default.
• W1600721449 hasRelatedWork W2090866443 @default.
• W1600721449 hasRelatedWork W2142996185 @default.
• W1600721449 hasRelatedWork W2203827900 @default.
• W1600721449 hasRelatedWork W2409547944 @default.
• W1600721449 hasRelatedWork W2472264334 @default.
• W1600721449 hasRelatedWork W2558657092 @default.
• W1600721449 hasRelatedWork W2890392355 @default.
• W1600721449 hasRelatedWork W2304141302 @default.
• W1600721449 isParatext "false" @default.
• W1600721449 isRetracted "false" @default.
• W1600721449 magId "1600721449" @default.
• W1600721449 workType "article" @default.