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- W1601069304 abstract "Previously observed (JAPCA 38:28-35, 1988) pulmonary responses of ΔFEV, (−13%), moderate to severe pain upon inspiration, and a doubling of PD100 for aethacholine following prolonged moderate exercise at 0.12 ppm O3 were of sufficient Magnitude to warrant our assessing responses at a lover range of concentrations, i.e., 0.08, 0.10 and 0.12 ppm O3. Exposures consisted of six 50-nin exercises (VE =40 L/min), each followed by 10-min rest; a 35-min lunch break vas included. Then compared with exposures to 0.00 ppa, substantial pulmonary function decrements, respiratory symptoms and increases in nonspecific airway reactivity were observed at all three 0- concentrations. For example, decreases in FEV. (P < 0.01) of 7%, 7%and 121 vere observed at 0.08, 0.10 and 0.12 ppa 0-, respectively. The ratios (P < 0.005) of PD100 observed in 0.00 ppa to that in 0, were 1.56 at 0.08 ppa, 1.89 at 0.10 ppa, ana 2.21 at 0.12 ppa O3. Ve conclude that exercise representative of a day of moderate to heavy vork or play performed during exposures to 0- at levels and pattern often found in ambient air induced clinically meaningful pulmonary responses." @default.
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- W1601069304 date "1989-01-01" @default.
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- W1601069304 title "Changes in Pulmonary Function and Airway Reactivity Due to Prolonged Exposure to Typical Ambient Ozone (O3) Levels" @default.
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- W1601069304 doi "https://doi.org/10.1016/s0166-1116(08)70639-3" @default.
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