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- W1601782197 abstract "In this paper recent results on random graphs are used as a framework for a theory of mutation based computation. The paradigm for mutation based computation will be the evolution of molecular structures. The mathematical structure of {open_quotes}folding maps{close_quotes} into molecular structures is shown to guarantee an effective search by point-mutations. Detailed mathematical models for these mappings are discussed. We will show that combinatorial structures consisting of (i) a (random) contact graph and (ii) a family of relations imposed on its adjacent vertices allow for efficient search by point mutations. We will determine the graph structure of the contact-graph and discuss its relation to the optimization process. Mappings of sequences into random structure is modeled as a random graph in sequence space, the neutral network. We will analyze the graph structure of neutral networks and show how they are embedded in sequence space. Explicitely we discuss connectivity and density of neutral networks and prove that any two neutral networks come close in sequence space. Finally several experiments are shown that illustrate the prospective of using this molecular computation method." @default.
- W1601782197 created "2016-06-24" @default.
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- W1601782197 date "1997-08-01" @default.
- W1601782197 modified "2023-09-27" @default.
- W1601782197 title "Mutation and molecules towards mutation-based computation" @default.
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