Matches in SemOpenAlex for { <https://semopenalex.org/work/W1601956019> ?p ?o ?g. }
- W1601956019 endingPage "250" @default.
- W1601956019 startingPage "240" @default.
- W1601956019 abstract "Using the French claims database (Système National d'Information Inter-Régimes de l'Assurance Maladie) linked to the hospital discharge database (Programme de Médicalisation des Systèmes d'Information), this observational study compared the effectiveness of rosuvastatin and simvastatin prescribed at doses with close LDL-cholesterol-lowering potency on all-cause mortality and cardiovascular and cerebrovascular diseases (CCDs) in primary prevention.This historical cohort included patients with no prior CCD, aged 40-79 years, who initiated statin therapy with rosuvastatin 5 mg or simvastatin 20 mg in 2008-2009 in general practice. Follow-up started after a 1-year period used to select patients who regularly received the initial treatment. In an intention-to-treat analysis, patients were followed up to December 2011. In a per-protocol analysis, they were censored prematurely when they discontinued their initial treatment. Adjustment for baseline covariates (age, deprivation index, comedications, comorbidities, prior hospital admissions) was carried out by a Cox proportional hazards model. In the per-protocol analysis, estimation was done by inverse probability of censoring weighting using additional time-dependent covariates. Analyses were gender-specific.A total of 106941 patients initiated statin therapy with rosuvastatin 5 mg and 56860 with simvastatin 20 mg. Mean follow-up was 35.8 months. For both genders and both types of analyses, the difference in incidence rates of mortality and/or CCD between rosuvastatin 5 mg and simvastatin 20 mg users was not statistically significant after adjustment (e.g., for CCD and/or mortality in men, in intention-to-treat analysis HR=0.94 [95% CI=0.85-1.04], in per-protocol analysis HR=0.98 [0.87-1.10]).The results of this real-life study based on medico-administrative databases do not support preferential prescription of rosuvastatin compared to simvastatin for primary prevention of CCD." @default.
- W1601956019 created "2016-06-24" @default.
- W1601956019 creator A5021605461 @default.
- W1601956019 creator A5055912652 @default.
- W1601956019 creator A5073848354 @default.
- W1601956019 creator A5080099253 @default.
- W1601956019 creator A5082932725 @default.
- W1601956019 creator A5088214034 @default.
- W1601956019 date "2013-12-02" @default.
- W1601956019 modified "2023-10-06" @default.
- W1601956019 title "Comparative effectiveness of rosuvastatin versus simvastatin in primary prevention among new users: a cohort study in the French national health insurance database" @default.
- W1601956019 cites W1502524639 @default.
- W1601956019 cites W1570622790 @default.
- W1601956019 cites W161660362 @default.
- W1601956019 cites W1743994462 @default.
- W1601956019 cites W1816597323 @default.
- W1601956019 cites W1863726591 @default.
- W1601956019 cites W1965012182 @default.
- W1601956019 cites W1997007231 @default.
- W1601956019 cites W2007986154 @default.
- W1601956019 cites W2008557562 @default.
- W1601956019 cites W2016722530 @default.
- W1601956019 cites W2016895882 @default.
- W1601956019 cites W2018711158 @default.
- W1601956019 cites W2026541116 @default.
- W1601956019 cites W2031185570 @default.
- W1601956019 cites W2048859524 @default.
- W1601956019 cites W2051030657 @default.
- W1601956019 cites W2054387099 @default.
- W1601956019 cites W2054558404 @default.
- W1601956019 cites W2057674977 @default.
- W1601956019 cites W2059793614 @default.
- W1601956019 cites W2062359643 @default.
- W1601956019 cites W2071066672 @default.
- W1601956019 cites W2071891597 @default.
- W1601956019 cites W2083707390 @default.
- W1601956019 cites W2086817119 @default.
- W1601956019 cites W2100800328 @default.
- W1601956019 cites W2102371553 @default.
- W1601956019 cites W2104344587 @default.
- W1601956019 cites W2105592956 @default.
- W1601956019 cites W2110171695 @default.
- W1601956019 cites W2117508744 @default.
- W1601956019 cites W2118243287 @default.
- W1601956019 cites W2128840214 @default.
- W1601956019 cites W2134071773 @default.
- W1601956019 cites W2135194195 @default.
- W1601956019 cites W2137983259 @default.
- W1601956019 cites W2139168645 @default.
- W1601956019 cites W2141465482 @default.
- W1601956019 cites W2148168402 @default.
- W1601956019 cites W2152237207 @default.
- W1601956019 cites W2152954903 @default.
- W1601956019 cites W2154704322 @default.
- W1601956019 cites W2155598961 @default.
- W1601956019 cites W2155693224 @default.
- W1601956019 cites W2155784627 @default.
- W1601956019 cites W2159449551 @default.
- W1601956019 cites W2160810969 @default.
- W1601956019 cites W2165412221 @default.
- W1601956019 cites W2166910397 @default.
- W1601956019 cites W2247997571 @default.
- W1601956019 cites W2322095705 @default.
- W1601956019 cites W2787894218 @default.
- W1601956019 doi "https://doi.org/10.1002/pds.3544" @default.
- W1601956019 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4265280" @default.
- W1601956019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24292987" @default.
- W1601956019 hasPublicationYear "2013" @default.
- W1601956019 type Work @default.
- W1601956019 sameAs 1601956019 @default.
- W1601956019 citedByCount "23" @default.
- W1601956019 countsByYear W16019560192014 @default.
- W1601956019 countsByYear W16019560192015 @default.
- W1601956019 countsByYear W16019560192016 @default.
- W1601956019 countsByYear W16019560192017 @default.
- W1601956019 countsByYear W16019560192018 @default.
- W1601956019 countsByYear W16019560192019 @default.
- W1601956019 countsByYear W16019560192020 @default.
- W1601956019 countsByYear W16019560192021 @default.
- W1601956019 countsByYear W16019560192022 @default.
- W1601956019 crossrefType "journal-article" @default.
- W1601956019 hasAuthorship W1601956019A5021605461 @default.
- W1601956019 hasAuthorship W1601956019A5055912652 @default.
- W1601956019 hasAuthorship W1601956019A5073848354 @default.
- W1601956019 hasAuthorship W1601956019A5080099253 @default.
- W1601956019 hasAuthorship W1601956019A5082932725 @default.
- W1601956019 hasAuthorship W1601956019A5088214034 @default.
- W1601956019 hasBestOaLocation W16019560191 @default.
- W1601956019 hasConcept C120665830 @default.
- W1601956019 hasConcept C121332964 @default.
- W1601956019 hasConcept C126322002 @default.
- W1601956019 hasConcept C137668524 @default.
- W1601956019 hasConcept C142724271 @default.
- W1601956019 hasConcept C17923572 @default.
- W1601956019 hasConcept C201903717 @default.
- W1601956019 hasConcept C23276603 @default.
- W1601956019 hasConcept C2426938 @default.
- W1601956019 hasConcept C2776329913 @default.