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• W1602027235 abstract "The aim of the present study was to evaluate quantitative micronuclei (MN) in the lining oral mucosa from chemical dependent patients. The MN originated from small extranucleus separated from the main one during cellular division. MN may appear before any clinical change is evident. Patients were divided in two groups: 24 chemical dependent patients, from CAPSAD (Centro de Apoio Psicosocial Alcool Drogas) Sao Jose dos Campos city and 24 control group patients from FOSJC-UNESP. Inclusion criterion for control group was nonsmoking for last 10 years, alcoholic beverages consumption of 03 units maximum per week, no drugs and no visible clinical alteration of the oral mucosa. Exfoliative cytology from the left side of the border of the tongue and MN test were performed. Feulgen staining was used and 600 cells were evaluated for each subject and analyzed under optical microscopies. To determinate the frequency of MN and micronucleated cells the statistical analysis used Kruskal-Wallis and MannWhitney tests, and Spearman correlation to determinate quantity and years of consumption (IC 95%). The incidence of MN in the CAPSAD group was 3,08 ± 3,20 and in the control group was 2,08 ± 1,93. The frequency of micronucleated buccal cells was 2,38 ± 2,57 to CAPSAD and 1,42 ± 1,25 to control group. The results showed that the micronuclei frequency and micronucleated buccal cells of CAPSAD group was increased but not statistically significant different from control group. The daily quantity consumption of cigarrete, alcohol and drugs presented effect of MN frequency higher than years of consumption." @default.
• W1602027235 created "2016-06-24" @default.
• W1602027235 creator A5066146698 @default.
• W1602027235 date "2007-07-31" @default.
• W1602027235 modified "2023-09-24" @default.
• W1602027235 title "Avaliação quantitativa de micronúcleos na citologia esfoliativa da mucosa bucal de pacientes dependentes químicos" @default.
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