FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1602164018> ?p ?o ?g. }

• W1602164018 endingPage "168" @default.
• W1602164018 startingPage "162" @default.
• W1602164018 abstract "Deep inspiration breath hold (DIBH) dramatically reduces radiation dose to the heart during radiation therapy (RT) for left-sided breast cancer, but the subsequent risk of radiation-related ischemic heart disease (IHD) is unknown. Our primary objective was to quantify the risk of IHD following RT with DIBH using modeled risk estimates (MRE).Patients with stage 0-III left-sided breast cancer who received RT with DIBH were retrospectively studied. Computed tomography simulations were performed with DIBH and during free breathing (FB) for comparison of dosimetry. Patients were classified as high risk, at risk, or at optimal risk for IHD and baseline risk estimates for IHD were obtained from historic controls. The excess relative risk of IHD because of left breast RT was calculated using patient-specific dosimetry and an existing dose-effect model. MRE were determined from the sum of baseline risk estimates and excess risk.Between 2002 and 2011, 111 patients were treated using DIBH and 104 were available for analysis. MRE for 10-year risk of IHD with DIBH and FB were 3.25% (interquartile range [IQR], 1.20-3.44) and 3.64% (IQR, 1.43-3.81) (P < .0001), respectively. MRE for lifetime risk of IHD with DIBH and FB were 9.71% (IQR, 1.98-16.62) and 10.28% (IQR, 2.05-16.97) (P < .0001), respectively. MRE were significantly reduced by use of DIBH in all risk groups. The largest absolute risk reduction resulting from the DIBH technique was observed in patients at high risk for IHD. The median relative risk reduction in MRE resulting from DIBH was 11.4% (range, 0-32.0) and 6.4% (range, 0-23.4) at 10 years and throughout the patients' lifetime, respectively. After a median follow-up of 7.0 years (range, 1.3-11.2), the estimated 10-year freedom from IHD was 99.0% (95% confidence interval 93.4-99.8).RT with DIBH may provide breast cancer survivors a clinically significant reduction in the risk of IHD." @default.
• W1602164018 created "2016-06-24" @default.
• W1602164018 creator A5017651988 @default.
• W1602164018 creator A5026724923 @default.
• W1602164018 creator A5030855173 @default.
• W1602164018 creator A5049018134 @default.
• W1602164018 creator A5060238737 @default.
• W1602164018 creator A5061905180 @default.
• W1602164018 creator A5061960454 @default.
• W1602164018 date "2015-05-01" @default.
• W1602164018 modified "2023-10-15" @default.
• W1602164018 title "Modeled risk of ischemic heart disease following left breast irradiation with deep inspiration breath hold" @default.
• W1602164018 cites W1966894528 @default.
• W1602164018 cites W1967498888 @default.
• W1602164018 cites W1977270178 @default.
• W1602164018 cites W1979643318 @default.
• W1602164018 cites W1981991635 @default.
• W1602164018 cites W1982795107 @default.
• W1602164018 cites W1984502501 @default.
• W1602164018 cites W1998115042 @default.
• W1602164018 cites W2017472326 @default.
• W1602164018 cites W2033600419 @default.
• W1602164018 cites W2035595347 @default.
• W1602164018 cites W2037625231 @default.
• W1602164018 cites W2065239239 @default.
• W1602164018 cites W2066617715 @default.
• W1602164018 cites W2073662365 @default.
• W1602164018 cites W2078007296 @default.
• W1602164018 cites W2083882781 @default.
• W1602164018 cites W2100025800 @default.
• W1602164018 cites W2119984740 @default.
• W1602164018 cites W2134258634 @default.
• W1602164018 cites W2142397820 @default.
• W1602164018 cites W2142586294 @default.
• W1602164018 cites W2154375587 @default.
• W1602164018 cites W2156003808 @default.
• W1602164018 cites W2158615473 @default.
• W1602164018 cites W3036643429 @default.
• W1602164018 doi "https://doi.org/10.1016/j.prro.2014.10.002" @default.
• W1602164018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25957186" @default.
• W1602164018 hasPublicationYear "2015" @default.
• W1602164018 type Work @default.
• W1602164018 sameAs 1602164018 @default.
• W1602164018 citedByCount "15" @default.
• W1602164018 countsByYear W16021640182015 @default.
• W1602164018 countsByYear W16021640182016 @default.
• W1602164018 countsByYear W16021640182017 @default.
• W1602164018 countsByYear W16021640182018 @default.
• W1602164018 countsByYear W16021640182020 @default.
• W1602164018 countsByYear W16021640182022 @default.
• W1602164018 countsByYear W16021640182023 @default.
• W1602164018 crossrefType "journal-article" @default.
• W1602164018 hasAuthorship W1602164018A5017651988 @default.
• W1602164018 hasAuthorship W1602164018A5026724923 @default.
• W1602164018 hasAuthorship W1602164018A5030855173 @default.
• W1602164018 hasAuthorship W1602164018A5049018134 @default.
• W1602164018 hasAuthorship W1602164018A5060238737 @default.
• W1602164018 hasAuthorship W1602164018A5061905180 @default.
• W1602164018 hasAuthorship W1602164018A5061960454 @default.
• W1602164018 hasConcept C119060515 @default.
• W1602164018 hasConcept C120195587 @default.
• W1602164018 hasConcept C121608353 @default.
• W1602164018 hasConcept C126322002 @default.
• W1602164018 hasConcept C126838900 @default.
• W1602164018 hasConcept C2908623805 @default.
• W1602164018 hasConcept C2989005 @default.
• W1602164018 hasConcept C44249647 @default.
• W1602164018 hasConcept C509974204 @default.
• W1602164018 hasConcept C530470458 @default.
• W1602164018 hasConcept C71924100 @default.
• W1602164018 hasConcept C75088862 @default.
• W1602164018 hasConceptScore W1602164018C119060515 @default.
• W1602164018 hasConceptScore W1602164018C120195587 @default.
• W1602164018 hasConceptScore W1602164018C121608353 @default.
• W1602164018 hasConceptScore W1602164018C126322002 @default.
• W1602164018 hasConceptScore W1602164018C126838900 @default.
• W1602164018 hasConceptScore W1602164018C2908623805 @default.
• W1602164018 hasConceptScore W1602164018C2989005 @default.
• W1602164018 hasConceptScore W1602164018C44249647 @default.
• W1602164018 hasConceptScore W1602164018C509974204 @default.
• W1602164018 hasConceptScore W1602164018C530470458 @default.
• W1602164018 hasConceptScore W1602164018C71924100 @default.
• W1602164018 hasConceptScore W1602164018C75088862 @default.
• W1602164018 hasIssue "3" @default.
• W1602164018 hasLocation W16021640181 @default.
• W1602164018 hasLocation W16021640182 @default.
• W1602164018 hasOpenAccess W1602164018 @default.
• W1602164018 hasPrimaryLocation W16021640181 @default.
• W1602164018 hasRelatedWork W1602164018 @default.
• W1602164018 hasRelatedWork W1998608334 @default.
• W1602164018 hasRelatedWork W2061253854 @default.
• W1602164018 hasRelatedWork W2340860679 @default.
• W1602164018 hasRelatedWork W2349893790 @default.
• W1602164018 hasRelatedWork W2384708512 @default.
• W1602164018 hasRelatedWork W2971392718 @default.
• W1602164018 hasRelatedWork W3037686638 @default.
• W1602164018 hasRelatedWork W3162511055 @default.
• W1602164018 hasRelatedWork W3209446764 @default.

• next