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- W1602247016 abstract "Abstract New oral anticoagulants have changed the paradigm of anticoagulation management, improving patient convenience as well as possibly reducing the incidence of spontaneous intracranial haemorrhage. However, concerns remain regarding these agents due to the lack of monitoring capacity and availability of readily accessible specific antidotes. This is particularly pertinent in the older population, specifically the frail elderly, who have multiple comorbidities, higher risk of falls requiring intervention and increased risk of bleeding. This group has not been specifically studied in randomised controlled trials and hence extrapolation of trial data to this population should be done carefully. No national guidelines exist for the safe prescription and monitoring of new oral anticoagulants in frail older people. In this article, we provide a review of the currently available new oral anticoagulants in Australia, with a geriatric haematological perspective, including evidence from clinical trials and subsequent meta‐analyses, the concerns regarding these new agents, and how these impact on the older population." @default.
- W1602247016 created "2016-06-24" @default.
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- W1602247016 date "2015-06-01" @default.
- W1602247016 modified "2023-10-17" @default.
- W1602247016 title "New oral anticoagulants: an approach in older people" @default.
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- W1602247016 doi "https://doi.org/10.1002/jppr.1104" @default.
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