Matches in SemOpenAlex for { <https://semopenalex.org/work/W1602419707> ?p ?o ?g. }
- W1602419707 endingPage "73" @default.
- W1602419707 startingPage "21" @default.
- W1602419707 abstract "Natural products such as plant extracts and complex microbial secondary metabolites have recently attracted the attention of scientific world for their potential use as drugs for treating chronic diseases such as Type II diabetes. Non-Insulin-Dependent Diabetes Mellitus (NIDDM) or Type II diabetes has complicated basis and has various treatment options, each targeting different mechanism of action. One such option relies on digestive enzyme inhibition. Almost all of the currently used clinically digestive enzyme inhibitors are bacterial secondary metabolites. However in most cases understanding of their complete biosynthetic pathways remains a challenge. The currently used digestive enzyme inhibitors have significant side effects that have restricted their usage. Hence, many active plant metabolites are being investigated as more effective treatment with fewer side effects. Flavonoids, terpenoids, glycosides are few to name in that class. Many of these are proven inhibitors of digestive enzymes but their large scale production remains a technical conundrum. Their successful heterologous production in simple host bacteria in scalable quantities gives a new dimension to the continuously active research for better treatment for type II diabetes. Looking at existing and new methods of mass level production of digestive inhibitors and latest efforts to effectively discover new potential drugs is the subject of this book chapter." @default.
- W1602419707 created "2016-06-24" @default.
- W1602419707 creator A5006965980 @default.
- W1602419707 creator A5056167556 @default.
- W1602419707 creator A5068845184 @default.
- W1602419707 date "2010-01-01" @default.
- W1602419707 modified "2023-10-13" @default.
- W1602419707 title "Natural Products for Type II Diabetes Treatment" @default.
- W1602419707 cites W143876065 @default.
- W1602419707 cites W1524482367 @default.
- W1602419707 cites W16265962 @default.
- W1602419707 cites W1795126892 @default.
- W1602419707 cites W1824143413 @default.
- W1602419707 cites W1931911624 @default.
- W1602419707 cites W1964699583 @default.
- W1602419707 cites W1965132968 @default.
- W1602419707 cites W1966048212 @default.
- W1602419707 cites W1968373028 @default.
- W1602419707 cites W1968513311 @default.
- W1602419707 cites W1969476532 @default.
- W1602419707 cites W1973806483 @default.
- W1602419707 cites W1984663723 @default.
- W1602419707 cites W1987672280 @default.
- W1602419707 cites W1987679117 @default.
- W1602419707 cites W1988452035 @default.
- W1602419707 cites W1991881136 @default.
- W1602419707 cites W1996291920 @default.
- W1602419707 cites W1996531503 @default.
- W1602419707 cites W2000807195 @default.
- W1602419707 cites W2000999406 @default.
- W1602419707 cites W2002372620 @default.
- W1602419707 cites W2003376788 @default.
- W1602419707 cites W2003786234 @default.
- W1602419707 cites W2004212059 @default.
- W1602419707 cites W2004304611 @default.
- W1602419707 cites W2005208228 @default.
- W1602419707 cites W2007677170 @default.
- W1602419707 cites W2009697783 @default.
- W1602419707 cites W2009931004 @default.
- W1602419707 cites W2013173608 @default.
- W1602419707 cites W2013332068 @default.
- W1602419707 cites W2013560821 @default.
- W1602419707 cites W2013843275 @default.
- W1602419707 cites W2016379859 @default.
- W1602419707 cites W2016786240 @default.
- W1602419707 cites W2017520661 @default.
- W1602419707 cites W2018001558 @default.
- W1602419707 cites W2019924845 @default.
- W1602419707 cites W2021233703 @default.
- W1602419707 cites W2021967628 @default.
- W1602419707 cites W2023032541 @default.
- W1602419707 cites W2024165279 @default.
- W1602419707 cites W2024172008 @default.
- W1602419707 cites W2024459080 @default.
- W1602419707 cites W2027935771 @default.
- W1602419707 cites W2028038659 @default.
- W1602419707 cites W2032562855 @default.
- W1602419707 cites W2032996294 @default.
- W1602419707 cites W2034725283 @default.
- W1602419707 cites W2035061435 @default.
- W1602419707 cites W2036017077 @default.
- W1602419707 cites W2036131628 @default.
- W1602419707 cites W2039006908 @default.
- W1602419707 cites W2043330399 @default.
- W1602419707 cites W2044823323 @default.
- W1602419707 cites W2046395976 @default.
- W1602419707 cites W2046595505 @default.
- W1602419707 cites W2046738465 @default.
- W1602419707 cites W2047541093 @default.
- W1602419707 cites W2048298541 @default.
- W1602419707 cites W2049049563 @default.
- W1602419707 cites W2049067099 @default.
- W1602419707 cites W2049075991 @default.
- W1602419707 cites W2050271315 @default.
- W1602419707 cites W2051956627 @default.
- W1602419707 cites W2052990434 @default.
- W1602419707 cites W2058258002 @default.
- W1602419707 cites W2059419260 @default.
- W1602419707 cites W2062037813 @default.
- W1602419707 cites W2062347046 @default.
- W1602419707 cites W2066659788 @default.
- W1602419707 cites W2067338816 @default.
- W1602419707 cites W2069935741 @default.
- W1602419707 cites W2070261059 @default.
- W1602419707 cites W2071621311 @default.
- W1602419707 cites W2072432880 @default.
- W1602419707 cites W2072985846 @default.
- W1602419707 cites W2073952281 @default.
- W1602419707 cites W2075365208 @default.
- W1602419707 cites W2077716285 @default.
- W1602419707 cites W2082767535 @default.
- W1602419707 cites W2082915038 @default.
- W1602419707 cites W2083025941 @default.
- W1602419707 cites W2084464906 @default.
- W1602419707 cites W2086795949 @default.
- W1602419707 cites W2087446674 @default.
- W1602419707 cites W2087856900 @default.
- W1602419707 cites W2089005129 @default.