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- W1602775391 abstract "Research Article1 January 1985free access Structure and expression of the human haptoglobin locus. G. Bensi G. Bensi Search for more papers by this author G. Raugei G. Raugei Search for more papers by this author H. Klefenz H. Klefenz Search for more papers by this author R. Cortese R. Cortese Search for more papers by this author G. Bensi G. Bensi Search for more papers by this author G. Raugei G. Raugei Search for more papers by this author H. Klefenz H. Klefenz Search for more papers by this author R. Cortese R. Cortese Search for more papers by this author Author Information G. Bensi, G. Raugei, H. Klefenz and R. Cortese The EMBO Journal (1985)4:119-126https://doi.org/10.1002/j.1460-2075.1985.tb02325.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info Human genomic clones of the haptoglobin Hp1F and the ‘haptoglobin related’ gene (Hpr) have been isolated. The two genes are adjacent, spanning a region of approximately 21 kb. A comparison of their coding sequences shows that Hpr differs from Hp1F at 28 codons. Northern blot and primer elongation analyses with human liver RNA show that the haptoglobin gene Hp1F appears to be transcribed some 1000-fold less in fetal than in adult liver. In adult liver the amount of Hpr mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the Hp1F gene. No Hpr mRNA can be detected in fetal liver. Previous ArticleNext Article Volume 4Issue 11 January 1985In this issue RelatedDetailsLoading ..." @default.
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- W1602775391 title "Structure and expression of the human haptoglobin locus." @default.
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- W1602775391 doi "https://doi.org/10.1002/j.1460-2075.1985.tb02325.x" @default.
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