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- W160342859 abstract "Several biomarkers have been reported as predictors of survival and recurrence in non-small cell lung cancer. Recently, several groups have demonstrated that the immune microenvironment of the primary tumors is a prognostic factor. These immunological biomarkers in the tumor microenvironment are useful predictors of prognosis as well as promising targets for novel therapeutic approaches. Especially, tumor-infiltrating Treg cells are a powerful immunological biomarker, and possible mechanisms involved in the induction of tumor-infiltrating Treg cells are the expression of Cox-2, IL-12Rβ2 or the lack of IL7R on the tumor cells. These findings may pave the way for individualized immunomodulatory therapies to deplete tumor-infiltrating Treg cells from the tumor microenvironment." @default.
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- W160342859 date "2013-07-01" @default.
- W160342859 modified "2023-09-23" @default.
- W160342859 title "Clinical significance of the tumor microenvironment in non-small cell lung cancer." @default.
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- W160342859 doi "https://doi.org/10.3978/j.issn.2305-5839.2013.06.01" @default.
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