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- W1603594233 abstract "Knowledge of the basic structure of skin is necessary to understand the mechanisms of dermal absorption and toxicity of topically applied toxicants. Skin is an essential and dynamic organ. It is composed of three distinct layers: epidermis, dermis, and hypodermis. In addition to performing important functions including thermoregulation and preventing insensible water loss, it also has important metabolic, immunological, and neurosensory properties. However, the predominant function of skin is to protect the body against a variety of toxicological insults. Animals are relatively less protective against such insults as compared to humans because of a lack of clothing, inferior housing, and different social interactions. In most instances, the skin of animals directly contacts environmental, chemical, and other pollutant exposure without the benefit of manmade protection. Although the largest organ of the body can often face these insults to a certain threshold, animals exhibit symptoms of dermal toxicity when this limit is passed." @default.
- W1603594233 created "2016-06-24" @default.
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- W1603594233 date "2007-01-01" @default.
- W1603594233 modified "2023-09-26" @default.
- W1603594233 title "Dermal toxicity" @default.
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- W1603594233 doi "https://doi.org/10.1016/b978-012370467-2/50113-9" @default.
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