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- W1604087156 abstract "As a viscoelastic body, the cell exhibits both elastic and viscous characteristics (Kasza, 07). Although these mechanical properties have not been attributed wholly to a single element, such as the cytoskeletal network, the cytoplasm, the cell membrane, or the extracellular network (Janmey et al., 2007), it is agreed that they are determined predominantly by the cytoskeleton, a network of biopolymers in the form of actin filaments, microtubules, and intermediate filaments. The dynamic assembly and disassembly of these biopolymers give the cell the ability to move and to modulate its shape, elasticity, and mechanical strength in responses to mechanical and chemical stimuli from the external environment (Fletcher & Mullins, 2010). Among these cytoskeletal polymers, actin filaments are known to be primarily responsible for the rigidity of the cell. An increase in the concentration of actin filaments typically results in an increase in the rigidity of the cell, which can be characterized by Young’s modulus (Satcher Jr & Dewey Jr, 1996)." @default.
- W1604087156 created "2016-06-24" @default.
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- W1604087156 date "2012-11-07" @default.
- W1604087156 modified "2023-09-26" @default.
- W1604087156 title "Dynamic Mechanical Response of Epithelial Cells to Epidermal Growth Factor" @default.
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- W1604087156 doi "https://doi.org/10.5772/49977" @default.
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