FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1605168722> ?p ?o ?g. }

• W1605168722 endingPage "294" @default.
• W1605168722 startingPage "289" @default.
• W1605168722 abstract "ObjectiveRecent studies have demonstrated a high prevalence of multiresistant Mycobacterium tuberculosis (MDR-TB) in Saudi Arabia. In this study, we assessed the impact of this and other factors on the treatment outcome of tuberculosis among Saudi nationals.MethodsWe studied all patients (147 patients) with a culture-proven diagnosis of tuberculosis seen at the King Khalid National Guard Hospital (KKNGH), Jeddah, Saudi Arabia from June 1993 to June 1999. Treatment outcome was classified as success or failure based on the clinical assessment, improvement or deterioration of chest X-rays, and results of follow-up sputum examination.ResultsOf the 147 patients, only 126 completed the follow-up program. Treatment was found to be successful in 102 (81.0%) and unsuccessful in 24 (19.0%) of these 126 patients. However, treatment success is much less (102/147; 69.4%) and failure is much higher (45/147; 30.6%) if the 21 patients who were lost to follow-up are regarded as treatment failures. The prevalence of poor compliance and multiply drug-resistant Mycobacterium tuberculosis were found to be significantly higher among those with treatment failure than among those in whom treatment was successful. There was no significant difference in treatment outcome between the different age groups. However, failure of treatment was observed to be more common (P < 0.001) among males (35 patients; 46.7%) than among females (10 patients; 13.9%). This could be explained mainly by the significantly higher prevalence of non-compliance among males (44%) than among females (15.3%). There were no significant differences in the symptoms, radiologic findings, clinical presentation (pulmonary versus extrapulmonary), social background or drug resistance between genders.ConclusionSuccessful treatment outcome among Saudi Nationals seen at the KKNGH in 1993-99 was below the rate recommended by the WHO, and failed treatment was associated with poor compliance, male gender and drug-resistant Mycobacterium tuberculosis. These results emphasize the importance of culture and sensitivity tests for Mycobacterium tuberculosis and close supervision of patients taking antituberculosis medications. Recent studies have demonstrated a high prevalence of multiresistant Mycobacterium tuberculosis (MDR-TB) in Saudi Arabia. In this study, we assessed the impact of this and other factors on the treatment outcome of tuberculosis among Saudi nationals. We studied all patients (147 patients) with a culture-proven diagnosis of tuberculosis seen at the King Khalid National Guard Hospital (KKNGH), Jeddah, Saudi Arabia from June 1993 to June 1999. Treatment outcome was classified as success or failure based on the clinical assessment, improvement or deterioration of chest X-rays, and results of follow-up sputum examination. Of the 147 patients, only 126 completed the follow-up program. Treatment was found to be successful in 102 (81.0%) and unsuccessful in 24 (19.0%) of these 126 patients. However, treatment success is much less (102/147; 69.4%) and failure is much higher (45/147; 30.6%) if the 21 patients who were lost to follow-up are regarded as treatment failures. The prevalence of poor compliance and multiply drug-resistant Mycobacterium tuberculosis were found to be significantly higher among those with treatment failure than among those in whom treatment was successful. There was no significant difference in treatment outcome between the different age groups. However, failure of treatment was observed to be more common (P < 0.001) among males (35 patients; 46.7%) than among females (10 patients; 13.9%). This could be explained mainly by the significantly higher prevalence of non-compliance among males (44%) than among females (15.3%). There were no significant differences in the symptoms, radiologic findings, clinical presentation (pulmonary versus extrapulmonary), social background or drug resistance between genders. Successful treatment outcome among Saudi Nationals seen at the KKNGH in 1993-99 was below the rate recommended by the WHO, and failed treatment was associated with poor compliance, male gender and drug-resistant Mycobacterium tuberculosis. These results emphasize the importance of culture and sensitivity tests for Mycobacterium tuberculosis and close supervision of patients taking antituberculosis medications." @default.
• W1605168722 created "2016-06-24" @default.
• W1605168722 creator A5002671733 @default.
• W1605168722 creator A5031861251 @default.
• W1605168722 creator A5035141556 @default.
• W1605168722 creator A5050643416 @default.
• W1605168722 creator A5053848396 @default.
• W1605168722 creator A5066276824 @default.
• W1605168722 creator A5082839627 @default.
• W1605168722 creator A5087835083 @default.
• W1605168722 date "2003-04-01" @default.
• W1605168722 modified "2023-10-15" @default.
• W1605168722 title "Treatment outcome of tuberculosis among Saudi nationals: role of drug resistance and compliance" @default.
• W1605168722 cites W1973502713 @default.
• W1605168722 cites W1983033583 @default.
• W1605168722 cites W2007818460 @default.
• W1605168722 cites W2060420082 @default.
• W1605168722 cites W2107570846 @default.
• W1605168722 doi "https://doi.org/10.1046/j.1469-0691.2003.00547.x" @default.
• W1605168722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12667238" @default.
• W1605168722 hasPublicationYear "2003" @default.
• W1605168722 type Work @default.
• W1605168722 sameAs 1605168722 @default.
• W1605168722 citedByCount "30" @default.
• W1605168722 countsByYear W16051687222012 @default.
• W1605168722 countsByYear W16051687222013 @default.
• W1605168722 countsByYear W16051687222014 @default.
• W1605168722 countsByYear W16051687222015 @default.
• W1605168722 countsByYear W16051687222017 @default.
• W1605168722 countsByYear W16051687222018 @default.
• W1605168722 countsByYear W16051687222020 @default.
• W1605168722 countsByYear W16051687222022 @default.
• W1605168722 countsByYear W16051687222023 @default.
• W1605168722 crossrefType "journal-article" @default.
• W1605168722 hasAuthorship W1605168722A5002671733 @default.
• W1605168722 hasAuthorship W1605168722A5031861251 @default.
• W1605168722 hasAuthorship W1605168722A5035141556 @default.
• W1605168722 hasAuthorship W1605168722A5050643416 @default.
• W1605168722 hasAuthorship W1605168722A5053848396 @default.
• W1605168722 hasAuthorship W1605168722A5066276824 @default.
• W1605168722 hasAuthorship W1605168722A5082839627 @default.
• W1605168722 hasAuthorship W1605168722A5087835083 @default.
• W1605168722 hasBestOaLocation W16051687221 @default.
• W1605168722 hasConcept C114851261 @default.
• W1605168722 hasConcept C126322002 @default.
• W1605168722 hasConcept C141071460 @default.
• W1605168722 hasConcept C142724271 @default.
• W1605168722 hasConcept C2776301714 @default.
• W1605168722 hasConcept C2777975735 @default.
• W1605168722 hasConcept C2779912665 @default.
• W1605168722 hasConcept C2781069245 @default.
• W1605168722 hasConcept C71924100 @default.
• W1605168722 hasConcept C86803240 @default.
• W1605168722 hasConcept C89423630 @default.
• W1605168722 hasConceptScore W1605168722C114851261 @default.
• W1605168722 hasConceptScore W1605168722C126322002 @default.
• W1605168722 hasConceptScore W1605168722C141071460 @default.
• W1605168722 hasConceptScore W1605168722C142724271 @default.
• W1605168722 hasConceptScore W1605168722C2776301714 @default.
• W1605168722 hasConceptScore W1605168722C2777975735 @default.
• W1605168722 hasConceptScore W1605168722C2779912665 @default.
• W1605168722 hasConceptScore W1605168722C2781069245 @default.
• W1605168722 hasConceptScore W1605168722C71924100 @default.
• W1605168722 hasConceptScore W1605168722C86803240 @default.
• W1605168722 hasConceptScore W1605168722C89423630 @default.
• W1605168722 hasIssue "4" @default.
• W1605168722 hasLocation W16051687221 @default.
• W1605168722 hasLocation W16051687222 @default.
• W1605168722 hasOpenAccess W1605168722 @default.
• W1605168722 hasPrimaryLocation W16051687221 @default.
• W1605168722 hasRelatedWork W1538374398 @default.
• W1605168722 hasRelatedWork W195559998 @default.
• W1605168722 hasRelatedWork W2042252940 @default.
• W1605168722 hasRelatedWork W2050407936 @default.
• W1605168722 hasRelatedWork W2110949356 @default.
• W1605168722 hasRelatedWork W2367868412 @default.
• W1605168722 hasRelatedWork W2411061500 @default.
• W1605168722 hasRelatedWork W2972094210 @default.
• W1605168722 hasRelatedWork W4210506554 @default.
• W1605168722 hasRelatedWork W4308058527 @default.
• W1605168722 hasVolume "9" @default.
• W1605168722 isParatext "false" @default.
• W1605168722 isRetracted "false" @default.
• W1605168722 magId "1605168722" @default.
• W1605168722 workType "article" @default.