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- W1605285201 abstract "Beta-oxidation of fatty acids and detoxification of reactive oxygen species are generally accepted as being fundamental functions of peroxisomes. Additionally, these pathways might have been the driving force favoring the selection of this compartment during eukaryotic evolution. Here we performed phylogenetic analyses of enzymes involved in beta-oxidation of fatty acids in Bacteria, Eukaryota, and Archaea. These imply an alpha-proteobacterial origin for three out of four enzymes. By integrating the enzymes' history into the contrasting models on the origin of eukaryotic cells, we conclude that peroxisomes most likely evolved non-symbiotically and subsequent to the acquisition of mitochondria in an archaeal host cell." @default.
- W1605285201 created "2016-06-24" @default.
- W1605285201 creator A5013318959 @default.
- W1605285201 creator A5047370853 @default.
- W1605285201 creator A5052008591 @default.
- W1605285201 date "2014-11-13" @default.
- W1605285201 modified "2023-09-23" @default.
- W1605285201 title "The evolution of eukaryotic cells from the perspective of peroxisomes" @default.
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- W1605285201 doi "https://doi.org/10.1002/bies.201400151" @default.
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