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- W1605330836 abstract "Investigation of the neural basis of memory and aging has moved to new levels in the 1990s as it has become evident that extensive neuronal loss in critical structures such as the hippocampus does not occur during normal aging. Extensive neuronal death, severe memory impairment, and dementia are concomitants of neuropathological diseases such as Alzheimer's disease, and the inclusion of participants in the early stages of these diseases in studies of normal aging probably misrepresented the extent of memory impairment in old age. Nevertheless, there is some age-related decline in the ability to acquire and retain new information. The form of effortful, conscious learning and memory called declarative memory is performed more poorly by older adults, and complaints about loss of these learning and memory skills are common in the older population. Some forms of learning and memory that can occur in the absence of awareness (called nondeclarative memory) are mildly affected, whereas other forms of nondeclarative memory are impaired in middle age. Aging affects the various brain memory systems differentially, impairing some components and sparing others. Electrophysiological and neurotransmitter mechanisms rather than cell loss have been associated with some forms of age-related memory impairment." @default.
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- W1605330836 date "2001-01-01" @default.
- W1605330836 modified "2023-09-27" @default.
- W1605330836 title "Memory and Aging, Neural Basis of" @default.
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- W1605330836 doi "https://doi.org/10.1016/b0-08-043076-7/03596-8" @default.
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