FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1605338936> ?p ?o ?g. }

• W1605338936 endingPage "1241" @default.
• W1605338936 startingPage "1234" @default.
• W1605338936 abstract "The diurnal pattern of DNA synthesis in young rats (28 to 35 days) was investigated under various feeding regimens of a normal and a protein-deficient diet. All animals were exposed to a 12-hour light-12-hour dark cycle. With ad libitum feeding of a stock diet, the incorporation of thymidine-3H into nuclear DNA in liver varied over a fivefold range with a peak at the end of the dark period, whereas incorporation into mitochondrial DNA scarcely varied. A diet deficient in protein (3.5% protein) not only decreased the incorporation of thymidine-3H into liver DNA but also obscured the diurnal peaks observed in animals fed a diet containing 26% protein. The activity of thymidine kinase was also depressed, but the diurnal peak was still discernible though slightly delayed. The effect of feeding schedule was then studied by restricting the feeding period of a stock diet to either the first 8 hours of the dark period (close to normal feeding behavior) or to the first 8 hours of light. The 12-hour difference in the feeding period resulted in a closely corresponding difference in the timing of the peak incorporation of thymidine-3H into DNA. In rats gradually adapted to a 4-hour feeding schedule over a period of 10 days, there was a briefer but prominent peak of incorporation about 12 hours after the onset of feeding. A smaller peak was concurrently present in the adrenals but in skeletal muscle, intestinal mucosa and bone marrow there was no clear pattern of deviation from the 24-hour mean values. The results indicate that 1) in contrast to nuclear DNA, there is no prominent diurnal peak of mitochondrial DNA synthesis in liver; 2) the peak of nuclear DNA synthesis in liver is obscured by a protein-deficient diet; 3) the peak follows feeding of a normal diet by about 12 hours, independently of the light-dark cycle; and 4) with the exception of the adrenals, other tissues studied did not reveal a food-dependent peak of DNA synthesis." @default.
• W1605338936 created "2016-06-24" @default.
• W1605338936 creator A5002044701 @default.
• W1605338936 creator A5035644071 @default.
• W1605338936 creator A5048390759 @default.
• W1605338936 date "1974-10-01" @default.
• W1605338936 modified "2023-10-16" @default.
• W1605338936 title "Diurnal Patterns of DNA Synthesis in the Rat: Modification by Diet and Feeding Schedule" @default.
• W1605338936 cites W1503716838 @default.
• W1605338936 cites W1820722613 @default.
• W1605338936 cites W1882000641 @default.
• W1605338936 cites W1936331802 @default.
• W1605338936 cites W1948189573 @default.
• W1605338936 cites W1975171772 @default.
• W1605338936 cites W2001060974 @default.
• W1605338936 cites W2024341430 @default.
• W1605338936 cites W2038015679 @default.
• W1605338936 cites W2045242994 @default.
• W1605338936 cites W2049022969 @default.
• W1605338936 cites W2051981569 @default.
• W1605338936 cites W2054826141 @default.
• W1605338936 cites W2080587133 @default.
• W1605338936 cites W39674681 @default.
• W1605338936 doi "https://doi.org/10.1093/jn/104.10.1234" @default.
• W1605338936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4472065" @default.
• W1605338936 hasPublicationYear "1974" @default.
• W1605338936 type Work @default.
• W1605338936 sameAs 1605338936 @default.
• W1605338936 citedByCount "27" @default.
• W1605338936 countsByYear W16053389362012 @default.
• W1605338936 countsByYear W16053389362014 @default.
• W1605338936 countsByYear W16053389362015 @default.
• W1605338936 countsByYear W16053389362019 @default.
• W1605338936 countsByYear W16053389362020 @default.
• W1605338936 crossrefType "journal-article" @default.
• W1605338936 hasAuthorship W1605338936A5002044701 @default.
• W1605338936 hasAuthorship W1605338936A5035644071 @default.
• W1605338936 hasAuthorship W1605338936A5048390759 @default.
• W1605338936 hasBestOaLocation W16053389361 @default.
• W1605338936 hasConcept C121332964 @default.
• W1605338936 hasConcept C121446783 @default.
• W1605338936 hasConcept C126322002 @default.
• W1605338936 hasConcept C127313418 @default.
• W1605338936 hasConcept C134018914 @default.
• W1605338936 hasConcept C140793950 @default.
• W1605338936 hasConcept C167678106 @default.
• W1605338936 hasConcept C24890656 @default.
• W1605338936 hasConcept C2522874641 @default.
• W1605338936 hasConcept C2776147627 @default.
• W1605338936 hasConcept C2777108182 @default.
• W1605338936 hasConcept C2781196997 @default.
• W1605338936 hasConcept C2781291010 @default.
• W1605338936 hasConcept C54355233 @default.
• W1605338936 hasConcept C552990157 @default.
• W1605338936 hasConcept C55493867 @default.
• W1605338936 hasConcept C64241487 @default.
• W1605338936 hasConcept C71924100 @default.
• W1605338936 hasConcept C86803240 @default.
• W1605338936 hasConcept C91586092 @default.
• W1605338936 hasConceptScore W1605338936C121332964 @default.
• W1605338936 hasConceptScore W1605338936C121446783 @default.
• W1605338936 hasConceptScore W1605338936C126322002 @default.
• W1605338936 hasConceptScore W1605338936C127313418 @default.
• W1605338936 hasConceptScore W1605338936C134018914 @default.
• W1605338936 hasConceptScore W1605338936C140793950 @default.
• W1605338936 hasConceptScore W1605338936C167678106 @default.
• W1605338936 hasConceptScore W1605338936C24890656 @default.
• W1605338936 hasConceptScore W1605338936C2522874641 @default.
• W1605338936 hasConceptScore W1605338936C2776147627 @default.
• W1605338936 hasConceptScore W1605338936C2777108182 @default.
• W1605338936 hasConceptScore W1605338936C2781196997 @default.
• W1605338936 hasConceptScore W1605338936C2781291010 @default.
• W1605338936 hasConceptScore W1605338936C54355233 @default.
• W1605338936 hasConceptScore W1605338936C552990157 @default.
• W1605338936 hasConceptScore W1605338936C55493867 @default.
• W1605338936 hasConceptScore W1605338936C64241487 @default.
• W1605338936 hasConceptScore W1605338936C71924100 @default.
• W1605338936 hasConceptScore W1605338936C86803240 @default.
• W1605338936 hasConceptScore W1605338936C91586092 @default.
• W1605338936 hasIssue "10" @default.
• W1605338936 hasLocation W16053389361 @default.
• W1605338936 hasLocation W16053389362 @default.
• W1605338936 hasOpenAccess W1605338936 @default.
• W1605338936 hasPrimaryLocation W16053389361 @default.
• W1605338936 hasRelatedWork W1605338936 @default.
• W1605338936 hasRelatedWork W1972296525 @default.
• W1605338936 hasRelatedWork W1978250152 @default.
• W1605338936 hasRelatedWork W1983217032 @default.
• W1605338936 hasRelatedWork W1986673839 @default.
• W1605338936 hasRelatedWork W2086585974 @default.
• W1605338936 hasRelatedWork W2092341993 @default.
• W1605338936 hasRelatedWork W2093538831 @default.
• W1605338936 hasRelatedWork W2101550646 @default.
• W1605338936 hasRelatedWork W2117909172 @default.
• W1605338936 hasVolume "104" @default.
• W1605338936 isParatext "false" @default.
• W1605338936 isRetracted "false" @default.
• W1605338936 magId "1605338936" @default.

• next