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- W1605697680 abstract "A corticosteroid with mixed glucocorticoid-mineralocorticoid actions was previously shown to improve neuromuscular function in muscular dystrophic chickens. The significance of that finding was recently underscored by reports that a mixed-action corticosteroid improved muscle function in Duchenne dystrophy patients, albeit at high doses. In the present study a pure glucocorticoid improved function and retarded muscle histopathology in the chicken, but a pure mineralocorticoid did not. These observations suggest that elucidation of mechanisms by which glucocorticoids beneficially affect dystrophic muscle could lead to development of more effective therapies." @default.
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- W1605697680 date "1988-08-01" @default.
- W1605697680 modified "2023-09-24" @default.
- W1605697680 title "Glucocorticoids in muscular dystrophy: beneficial effects of dexamethasone on avian myopathy" @default.
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- W1605697680 doi "https://doi.org/10.1096/fasebj.2.11.3396809" @default.
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