FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1606083505> ?p ?o ?g. }

• W1606083505 endingPage "170" @default.
• W1606083505 startingPage "164" @default.
• W1606083505 abstract "A heat-shock response is induced when cells are exposed to temperatures slightly higher than their optimal physiological temperature. This response is based on the synthesis of heat-shock proteins encoded by the heat-shock genes. A correlation between the increased thermotolerance and production of 70-kDa heat-shock protein (hsp70) has been observed in many organisms. We tested this hypothesis by transferring a Caenorhabditis elegans heat-inducible hsp70 A-encoding gene into the entomopathogenic nematodes Heterorhabditis bacteriophora Hp88. Successful transformation of the gene was confirmed by Southern blot hybridization and polymerase chain reaction. Our blot studies showed that the transgenic nematodes contained five to ten copies per genome of the introduced hsp70 A gene. hsp70 mRNA transcripts were detected in both wild-type and transgenic nematodes. Transcripts increased severalfold in transgenic nematodes upon heat shock. Infective juveniles of both transgenic and wild-type nematodes that exposed to a sublethal heat treatment (35°C) for 2 h followed by a normally lethal heat treatment (40°C) for 1 h. More than 90% of transgenic nematodes survived heat treatment, compared to 2% to 3% of the wild-type strain. Our observations establish that overexpression of hsp70 A gene resulted an enhanced thermotolerance in the transgenic nematodes. The transgenic nematodes displayed normal growth and development. J. Exp. Zool. 281:164–170, 1998. © 1998 Wiley-Liss, Inc." @default.
• W1606083505 created "2016-06-24" @default.
• W1606083505 creator A5019664521 @default.
• W1606083505 creator A5028628938 @default.
• W1606083505 creator A5053238316 @default.
• W1606083505 creator A5063132984 @default.
• W1606083505 date "1998-06-15" @default.
• W1606083505 modified "2023-09-27" @default.
• W1606083505 title "Thermal response ofHeterorhabditis bacteriophora transformed with theCaenorhabditis eleganshsp70 encoding gene" @default.
• W1606083505 cites W106780798 @default.
• W1606083505 cites W1586386058 @default.
• W1606083505 cites W1865160862 @default.
• W1606083505 cites W1972458635 @default.
• W1606083505 cites W1974719685 @default.
• W1606083505 cites W1988485459 @default.
• W1606083505 cites W1998002137 @default.
• W1606083505 cites W2001193423 @default.
• W1606083505 cites W2003088600 @default.
• W1606083505 cites W2014669590 @default.
• W1606083505 cites W2015842629 @default.
• W1606083505 cites W2017334338 @default.
• W1606083505 cites W2021938974 @default.
• W1606083505 cites W2021964203 @default.
• W1606083505 cites W2029739901 @default.
• W1606083505 cites W2039188025 @default.
• W1606083505 cites W2063450941 @default.
• W1606083505 cites W2066562421 @default.
• W1606083505 cites W2082729423 @default.
• W1606083505 cites W2087274128 @default.
• W1606083505 cites W2122163057 @default.
• W1606083505 cites W2137417707 @default.
• W1606083505 cites W2157929779 @default.
• W1606083505 cites W2165113979 @default.
• W1606083505 doi "https://doi.org/10.1002/(sici)1097-010x(19980615)281:3<164::aid-jez2>3.0.co;2-l" @default.
• W1606083505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9621437" @default.
• W1606083505 hasPublicationYear "1998" @default.
• W1606083505 type Work @default.
• W1606083505 sameAs 1606083505 @default.
• W1606083505 citedByCount "35" @default.
• W1606083505 countsByYear W16060835052012 @default.
• W1606083505 countsByYear W16060835052014 @default.
• W1606083505 countsByYear W16060835052015 @default.
• W1606083505 countsByYear W16060835052016 @default.
• W1606083505 countsByYear W16060835052017 @default.
• W1606083505 countsByYear W16060835052019 @default.
• W1606083505 countsByYear W16060835052021 @default.
• W1606083505 countsByYear W16060835052022 @default.
• W1606083505 crossrefType "journal-article" @default.
• W1606083505 hasAuthorship W1606083505A5019664521 @default.
• W1606083505 hasAuthorship W1606083505A5028628938 @default.
• W1606083505 hasAuthorship W1606083505A5053238316 @default.
• W1606083505 hasAuthorship W1606083505A5063132984 @default.
• W1606083505 hasConcept C102230213 @default.
• W1606083505 hasConcept C104317684 @default.
• W1606083505 hasConcept C133307689 @default.
• W1606083505 hasConcept C137984847 @default.
• W1606083505 hasConcept C150194340 @default.
• W1606083505 hasConcept C153911025 @default.
• W1606083505 hasConcept C177707886 @default.
• W1606083505 hasConcept C18903297 @default.
• W1606083505 hasConcept C204241405 @default.
• W1606083505 hasConcept C205260736 @default.
• W1606083505 hasConcept C2776415932 @default.
• W1606083505 hasConcept C2778830712 @default.
• W1606083505 hasConcept C2780004239 @default.
• W1606083505 hasConcept C49105822 @default.
• W1606083505 hasConcept C54355233 @default.
• W1606083505 hasConcept C68991219 @default.
• W1606083505 hasConcept C86803240 @default.
• W1606083505 hasConceptScore W1606083505C102230213 @default.
• W1606083505 hasConceptScore W1606083505C104317684 @default.
• W1606083505 hasConceptScore W1606083505C133307689 @default.
• W1606083505 hasConceptScore W1606083505C137984847 @default.
• W1606083505 hasConceptScore W1606083505C150194340 @default.
• W1606083505 hasConceptScore W1606083505C153911025 @default.
• W1606083505 hasConceptScore W1606083505C177707886 @default.
• W1606083505 hasConceptScore W1606083505C18903297 @default.
• W1606083505 hasConceptScore W1606083505C204241405 @default.
• W1606083505 hasConceptScore W1606083505C205260736 @default.
• W1606083505 hasConceptScore W1606083505C2776415932 @default.
• W1606083505 hasConceptScore W1606083505C2778830712 @default.
• W1606083505 hasConceptScore W1606083505C2780004239 @default.
• W1606083505 hasConceptScore W1606083505C49105822 @default.
• W1606083505 hasConceptScore W1606083505C54355233 @default.
• W1606083505 hasConceptScore W1606083505C68991219 @default.
• W1606083505 hasConceptScore W1606083505C86803240 @default.
• W1606083505 hasIssue "3" @default.
• W1606083505 hasLocation W16060835051 @default.
• W1606083505 hasLocation W16060835052 @default.
• W1606083505 hasOpenAccess W1606083505 @default.
• W1606083505 hasPrimaryLocation W16060835051 @default.
• W1606083505 hasRelatedWork W1606083505 @default.
• W1606083505 hasRelatedWork W2010932836 @default.
• W1606083505 hasRelatedWork W2073110228 @default.
• W1606083505 hasRelatedWork W2125408806 @default.
• W1606083505 hasRelatedWork W2127012271 @default.
• W1606083505 hasRelatedWork W2155311690 @default.
• W1606083505 hasRelatedWork W2353644607 @default.

• next