FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1606133259> ?p ?o ?g. }

• W1606133259 endingPage "57" @default.
• W1606133259 startingPage "49" @default.
• W1606133259 abstract "The Eudragit RS and polyethylene glycol 400 (PEG 400) blend polymer (EPG) membranes were prepared by the solvent casting method to pioneer a novel application of Eudragit RS to a thermo-sensitive material. The EPG membranes containing 2.5-10% PEG 400 (2.5-10% EPG) showed the glass transition temperatures (Tgs) around the body temperature (32-42 degrees C). Drug permeation studies through the EPG membranes were carried out using acetaminophen (AAP) and aminopyrine (AMP) as the model drugs. The permeability of AAP and AMP through the EPG membranes has been shown to be a discontinuous function of temperature, that is, their permeability increased steeply above the Tg of the membranes. The amount of AMP permeated at 42 degrees C was nearly eight times as much as that at 36 degrees C. Arrhenius plots of the steady-state permeability coefficient (P) of AAP indicated two straight lines that intersect at the Tg of the 10% EPG membrane. In the water uptake study for the 10% EPG membrane, the degree of the swelling for the membrane tended to increase with increasing temperature above the Tg of the membrane. The thermo-sensitive permeation mechanism for the EPG membranes might be based on the structure change of the membranes caused by the glass transition, so that the membranes could absorb more water. Considering the high biological safety of Eudragit RS and PEG 400, the EPG membranes might be used to develop a novel thermo-sensitive drug delivery system." @default.
• W1606133259 created "2016-06-24" @default.
• W1606133259 creator A5015219408 @default.
• W1606133259 creator A5059014917 @default.
• W1606133259 creator A5074541829 @default.
• W1606133259 creator A5077706331 @default.
• W1606133259 date "2005-01-01" @default.
• W1606133259 modified "2023-09-25" @default.
• W1606133259 title "Application of Eudragit RS to thermo-sensitive drug delivery systems" @default.
• W1606133259 cites W1482689713 @default.
• W1606133259 cites W1965854434 @default.
• W1606133259 cites W1966729229 @default.
• W1606133259 cites W1967164439 @default.
• W1606133259 cites W2005647085 @default.
• W1606133259 cites W2012428112 @default.
• W1606133259 cites W2042996690 @default.
• W1606133259 cites W2047948690 @default.
• W1606133259 cites W2051749006 @default.
• W1606133259 cites W2070073454 @default.
• W1606133259 cites W2075502309 @default.
• W1606133259 cites W2095502385 @default.
• W1606133259 cites W2113093248 @default.
• W1606133259 cites W2315818784 @default.
• W1606133259 doi "https://doi.org/10.1016/j.jconrel.2004.09.027" @default.
• W1606133259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15653133" @default.
• W1606133259 hasPublicationYear "2005" @default.
• W1606133259 type Work @default.
• W1606133259 sameAs 1606133259 @default.
• W1606133259 citedByCount "45" @default.
• W1606133259 countsByYear W16061332592012 @default.
• W1606133259 countsByYear W16061332592013 @default.
• W1606133259 countsByYear W16061332592014 @default.
• W1606133259 countsByYear W16061332592015 @default.
• W1606133259 countsByYear W16061332592016 @default.
• W1606133259 countsByYear W16061332592017 @default.
• W1606133259 countsByYear W16061332592018 @default.
• W1606133259 countsByYear W16061332592019 @default.
• W1606133259 countsByYear W16061332592021 @default.
• W1606133259 countsByYear W16061332592022 @default.
• W1606133259 crossrefType "journal-article" @default.
• W1606133259 hasAuthorship W1606133259A5015219408 @default.
• W1606133259 hasAuthorship W1606133259A5059014917 @default.
• W1606133259 hasAuthorship W1606133259A5074541829 @default.
• W1606133259 hasAuthorship W1606133259A5077706331 @default.
• W1606133259 hasConcept C10138342 @default.
• W1606133259 hasConcept C120882062 @default.
• W1606133259 hasConcept C122865956 @default.
• W1606133259 hasConcept C127413603 @default.
• W1606133259 hasConcept C155515750 @default.
• W1606133259 hasConcept C162324750 @default.
• W1606133259 hasConcept C178790620 @default.
• W1606133259 hasConcept C185592680 @default.
• W1606133259 hasConcept C188027245 @default.
• W1606133259 hasConcept C2776964284 @default.
• W1606133259 hasConcept C2778540859 @default.
• W1606133259 hasConcept C2780471494 @default.
• W1606133259 hasConcept C41625074 @default.
• W1606133259 hasConcept C42360764 @default.
• W1606133259 hasConcept C43617362 @default.
• W1606133259 hasConcept C50670333 @default.
• W1606133259 hasConcept C521977710 @default.
• W1606133259 hasConcept C54400483 @default.
• W1606133259 hasConcept C55493867 @default.
• W1606133259 hasConceptScore W1606133259C10138342 @default.
• W1606133259 hasConceptScore W1606133259C120882062 @default.
• W1606133259 hasConceptScore W1606133259C122865956 @default.
• W1606133259 hasConceptScore W1606133259C127413603 @default.
• W1606133259 hasConceptScore W1606133259C155515750 @default.
• W1606133259 hasConceptScore W1606133259C162324750 @default.
• W1606133259 hasConceptScore W1606133259C178790620 @default.
• W1606133259 hasConceptScore W1606133259C185592680 @default.
• W1606133259 hasConceptScore W1606133259C188027245 @default.
• W1606133259 hasConceptScore W1606133259C2776964284 @default.
• W1606133259 hasConceptScore W1606133259C2778540859 @default.
• W1606133259 hasConceptScore W1606133259C2780471494 @default.
• W1606133259 hasConceptScore W1606133259C41625074 @default.
• W1606133259 hasConceptScore W1606133259C42360764 @default.
• W1606133259 hasConceptScore W1606133259C43617362 @default.
• W1606133259 hasConceptScore W1606133259C50670333 @default.
• W1606133259 hasConceptScore W1606133259C521977710 @default.
• W1606133259 hasConceptScore W1606133259C54400483 @default.
• W1606133259 hasConceptScore W1606133259C55493867 @default.
• W1606133259 hasIssue "1" @default.
• W1606133259 hasLocation W16061332591 @default.
• W1606133259 hasLocation W16061332592 @default.
• W1606133259 hasOpenAccess W1606133259 @default.
• W1606133259 hasPrimaryLocation W16061332591 @default.
• W1606133259 hasRelatedWork W2048464827 @default.
• W1606133259 hasRelatedWork W2063102075 @default.
• W1606133259 hasRelatedWork W2125331446 @default.
• W1606133259 hasRelatedWork W2198124994 @default.
• W1606133259 hasRelatedWork W2516474985 @default.
• W1606133259 hasRelatedWork W2594672449 @default.
• W1606133259 hasRelatedWork W3083900215 @default.
• W1606133259 hasRelatedWork W3169886986 @default.
• W1606133259 hasRelatedWork W4381384968 @default.
• W1606133259 hasRelatedWork W4384524398 @default.
• W1606133259 hasVolume "102" @default.

• next