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- W1606996890 abstract "Summary The sera of guinea pigs that had been immunized with tubercle bacilli and had been challenged by intracardiac injection of OT 4 hr before death were effective in transferring cutaneous hypersensitivity to neutral recipient guinea pigs. The mediator was a γG 2 -immunoglobulin. The lesions that developed in recipients after intradermal injection of OT were considered to be the result of an antigen-antibody interaction of an Arthus or of cutaneous anaphylaxis type, rather than those of delyed hypersensitivity. The conclusion was based on the following observations: peak reactions occurred between 12 and 18 hr after skin testing; the histology was not characteristic of delayed hypersensitivity; positive transfers by serum factors could not be accomplished when delayed hypersensitivity to DNP-BGG was produced in donors; and PPD was incapable of eliciting a positive skin response in recipient guinea pigs that yielded positive test with OT." @default.
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- W1606996890 date "1968-04-01" @default.
- W1606996890 modified "2023-09-23" @default.
- W1606996890 title "Transfer of cutaneous hypersensitivity to tuberculin in the guinea pig by gamma G2 from immunized donors." @default.
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