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- W1607072882 abstract "The activities of ten lysosomal enzymes were assayed in more than 100 amniotic fluids. Wide variations in enzyme activity were found at any particular gestational age. However, various patterns of enzyme activity were apparent in relation to gestational age. Three enzymes, β-glucosidase, α-glucosidase, and α-arabinosidase, showed high initial values, falling rapidly to a very low level after 20 weeks' gestation. The enzymes β-glucuronidase and α-mannosidase showed a peak of activity at about 26 weeks, and N-acetyl-β-D-glucosaminidase and α-fucosidase had higher values at midgestation, declining toward term. Acid phosphatase exhibited no obvious pattern. Higher values of α-galactosidase and β-galactosidase were noted near term, but at all times the levels of these two enzymes were minimal. The findings are discussed in relation to possible sources of the enzymes and anternatal diagnosis of inborn errors of metabolism." @default.
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- W1607072882 date "1974-07-01" @default.
- W1607072882 modified "2023-09-26" @default.
- W1607072882 title "Lysosomal enzymes of amniotic fluid in relation to gestational age" @default.
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- W1607072882 doi "https://doi.org/10.1016/0002-9378(74)90096-9" @default.
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